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2-(1-Piperidyl)ethanol

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Identification
Molecular formula
C7H15NO
CAS number
2955-88-6
IUPAC name
2-(1-piperidyl)ethanol
State
State

The compound is typically in a liquid state at room temperature. It is stable under normal conditions but may degrade if exposed to air and moisture for extended periods.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
206.00
Boiling point (Kelvin)
479.15
General information
Molecular weight
115.21g/mol
Molar mass
115.1850g/mol
Density
1.0020g/cm3
Appearence

2-(1-Piperidyl)ethanol is a colorless to light yellow liquid. It has a hygroscopic nature and is soluble in water and organic solvents due to its polar hydroxy group and piperidine ring structure.

Comment on solubility

Solubility of 2-(1-piperidyl)ethanol

2-(1-piperidyl)ethanol, with its unique structure, exhibits intriguing solubility properties influenced by its functional groups. Here's a closer look at its solubility behavior:

  • Solvent Compatibility: This compound is generally soluble in polar solvents such as water, as well as in organic solvents like ethanol and methanol.
  • Hydrogen Bonding: The presence of hydroxyl (–OH) in its structure enhances its ability to form hydrogen bonds, further promoting solubility in aqueous solutions.
  • Chain Length Effects: The piperidine ring contributes to the overall solubility, but the ethyl chain may introduce slight hydrophobic character, which can influence solubility in non-polar solvents.
  • Temperature Sensitivity: Like many organic compounds, the solubility of 2-(1-piperidyl)ethanol may increase with temperature, allowing it to dissolve more readily at higher temperatures.

In summary, “solubility is a complex interplay of molecular structure and environmental conditions.” The solubility profile of 2-(1-piperidyl)ethanol illustrates this principle, showcasing its potential applications in various chemical contexts.

Interesting facts

Interesting Facts about 2-(1-piperidyl)ethanol

2-(1-piperidyl)ethanol is quite a fascinating compound known for its various applications and properties that make it noteworthy in the world of chemistry. Here are some interesting aspects of this compound:

  • Functional Group Diversity: This compound features a hydroxyl group (-OH) and a piperidine ring, which enhances its reactivity and biological significance.
  • Potential Pharmacological Activity: Due to its piperidine structure, 2-(1-piperidyl)ethanol has garnered interest in medicinal chemistry. Compounds with similar structures have been found to exhibit a range of pharmacological activities, including analgesic and anti-inflammatory effects.
  • Solvent Properties: The alcohol group makes this compound a useful solvent in synthetic chemistry, beneficial for dissolving various organic compounds in laboratory settings.
  • Building Block in Synthesis: Scientists utilize 2-(1-piperidyl)ethanol as a building block or intermediate in the synthesis of more complex molecules, particularly in drug discovery and development.
  • Research Applications: As researchers look for new therapeutic agents, the unique structure of 2-(1-piperidyl)ethanol makes it an attractive candidate for exploration in the search for innovative treatments.

In summary, 2-(1-piperidyl)ethanol is more than just a simple alcohol; it's a compound enriched with potential that captures the attention of chemists and pharmacologists alike. As the field of medicinal chemistry evolves, this compound might just play a pivotal role in the development of new and exciting pharmaceuticals!

Synonyms
3040-44-6
2-Piperidinoethanol
1-(2-Hydroxyethyl)piperidine
1-PIPERIDINEETHANOL
N-Piperidineethanol
N-Piperidinoethanol
beta-Piperidinoethanol
.beta.-Piperidinoethanol
NSC 3460
EINECS 221-244-6
1-Oxa-4-azaspiro(3.5)nonane (VAN)
BRN 0103390
VR81F07RX5
AI3-11737
NSC-3460
DTXSID4062808
5-20-02-00101 (Beilstein Handbook Reference)
1-Oxa-4-azaspiro(3.5)nonane
1-Oxa-4-azaspiro[3.5]nonane
DTXCID8038194
2-(piperidin-1-yl)ethanol
N-(2-Hydroxyethyl)piperidine
2-(1-Piperidinyl)ethanol
N-(Hydroxyethyl)piperidine
beta-Piperidylethanol
2-(Piperidin-1-Yl)Ethan-1-Ol
2-piperidin-1-ylethanol
MFCD00006512
hydroxyethylpiperidine
.beta.-Piperidylethanol
2-Piperidin-1-yl-ethanol
CHEBI:61238
Piperidineethanol
1-piperidine ethanol
UNII-VR81F07RX5
1-piperidinethanol
NSC3460
2-piperidino-1-ethanol
2-(1-piperidyl)ethanol
SCHEMBL8564
(2-hydroxyethyl) piperidine
2-(piperidine-1-yl)ethanol
2-piperidin-1-ylethan-1-ol
N-(2-Hydroxyethyl) piperidine
2-(1-piperidinyl)-1-ethanol
CHEMBL118227
N-(beta-hydroxyethyl)-piperidine
Piperidine, 1-(2-hydroxyethyl)
N-(.beta.-Hydroxyethyl)piperidine
BCP26656
AKOS000120091
CS-W013444
FP16835
HY-W012728
LF-0538
SB42932
SY009520
DB-003053
NS00022019
P0348
EN300-20588
D70541
1-(2-Hydroxyethyl)piperidine, ReagentPlus(R), 99%
Q27130918
Z104479032
1-(2-Hydroxyethyl)piperidine, Vetec(TM) reagent grade, 98%
b-Piperidinoethanol;1-(2-Hydroxyethyl)piperidine;2-(1-Piperidino)ethanol