Bromazepam | Solubility of Things

Identification

Molecular formula

C₁₄H₁₇Br₂N₃O₂

CAS number

1812-30-2

IUPAC name

2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate

State

At room temperature, bromazepam is a solid.

Melting point (Celsius)

157.00

Melting point (Kelvin)

430.10

Boiling point (Celsius)

459.10

Boiling point (Kelvin)

732.30

General information

Molecular weight

316.11g/mol

Molar mass

316.1060g/mol

Density

1.8000g/cm³

Appearence

Bromazepam typically appears as a white to yellowish crystalline powder.

Comment on solubility

Solubility of 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate

The solubility of 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate can be characterized by several key factors:

Polarity: This compound contains polar functional groups, which can contribute to its solubility in polar solvents such as water, albeit to a limited extent due to the presence of hydrophobic regions.
Hydrogen Bonding: The presence of capable NH and CO groups allows for potential hydrogen bonding with solvents, thus enhancing solubility under certain conditions.
Solvent Interaction: Ethanol and methanol may serve as effective solvents due to their polar nature and ability to interact with functional groups present in the molecule.
Temperature: Increased temperature generally improves solubility for many organic compounds, including this carbamate, potentially aiding dissolution in various solvents.

However, as with many organic compounds, the solubility can be variable, meaning that empirical testing is often essential. It is worth noting:

Some solubility may be lost in non-polar solvents, demonstrating a selectivity based on solvent type.
Due to steric hindrance from the ^2,6-dibromophenyl group, achieving high solubility may be challenging.

In summary, while 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate exhibits some degree of solubility in polar solvents, its behavior can be complex and influenced by various external factors.

Interesting facts

Exploring 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate

2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate is a fascinating compound within the realm of organic chemistry, primarily due to its unique structural characteristics and potential applications. Here are some interesting facts about this compound:

Structure: The compound contains a piperidine ring, which is known for its role in pharmacological agents, and a distinct carbamate functional group, both of which contribute to its biological activity.
Biological Relevance: Compounds like this one are essential in the design of various pharmaceuticals. Their unique properties often make them effective agents in treating a range of conditions, including neurological disorders.
Substituent Effects: The presence of the 2,6-dibromophenyl group provides interesting electronic and steric effects that could enhance the compound's binding affinity to biological targets, making it an object of study for medicinal chemists.
Synthesis: Creating this compound often involves sophisticated synthesis techniques, which can include the use of protection-deprotection strategies to ensure the integrity of sensitive functional groups during reaction steps.
Research Potential: As researchers continuously seek new compounds with enhanced efficacy, 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate stands out as a promising candidate that warrants further investigation in drug development.

In summary, the layered complexity of 2-(1-piperidyl)ethyl N-(2,6-dibromophenyl)carbamate not only underscores its significance in organic synthesis but also highlights its potential contributions to pharmacology and medicinal chemistry. As we delve deeper into its properties and mechanisms, we uncover the promise that such compounds hold in advancing human health.