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2-(1-piperidylsulfanyl)-1,3-benzothiazole

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Identification
Molecular formula
C12H12N2S2
CAS number
139306-10-8
IUPAC name
2-(1-piperidylsulfanyl)-1,3-benzothiazole
State
State

At room temperature, 2-(1-piperidylsulfanyl)-1,3-benzothiazole is typically found in a solid state.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
264.39g/mol
Molar mass
264.3940g/mol
Density
1.3000g/cm3
Appearence

The compound 2-(1-piperidylsulfanyl)-1,3-benzothiazole appears as a yellow to brown solid. It may be powdery or crystalline depending on the preparation method. The specific shade can vary depending on purity and the presence of impurities.

Comment on solubility

Solubility of 2-(1-piperidylsulfanyl)-1,3-benzothiazole

The compound 2-(1-piperidylsulfanyl)-1,3-benzothiazole exhibits interesting solubility characteristics that can affect its applications and behavior in various environments. Understanding its solubility is crucial for effective usage in chemical processes, pharmaceuticals, and research.

Key Points on Solubility:

  • Solvent Dependence: The solubility of this compound may vary significantly in different solvents. For example, it is more likely to dissolve in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol compared to polar protic solvents like water.
  • Temperature Influence: Like many compounds, the solubility of 2-(1-piperidylsulfanyl)-1,3-benzothiazole can be influenced by temperature, often increasing with rising temperature.
  • Functional Groups Role: The presence of the piperidyl and sulfanyl groups within the molecule can enhance its lipophilicity, potentially limiting its solubility in aqueous environments.
  • pH Level Impact: The solubility may also be affected by the pH of the solution, as ionizable functional groups can lead to varying degrees of solvation.

In summary, while 2-(1-piperidylsulfanyl)-1,3-benzothiazole does exhibit solubility in certain organic solvents, its performance in aqueous environments is limited, marking it as a compound with specific solubility criteria that need to be understood for practical applications. As they say, "one man's solvent is another man's barrier," and this is particularly true in the context of compound solubility.

Interesting facts

Interesting Facts about 2-(1-piperidylsulfanyl)-1,3-benzothiazole

2-(1-piperidylsulfanyl)-1,3-benzothiazole is a compound that has garnered attention in the fields of medicinal chemistry and pharmacology due to its intriguing structure and potential applications. Here are some noteworthy points about this fascinating compound:

  • Structural Composition: The compound contains a benzothiazole ring, which is a bicyclic structure known for its biological activity. The incorporation of a piperidine group adds to its pharmacological diversity.
  • Biological Activities: Compounds with a benzothiazole moiety have been associated with various biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. Research is ongoing to fully understand the scope of these therapeutic potentials.
  • Role in Drug Development: The unique combination of a sulfanyl group and a piperidine in this compound makes it a valuable candidate for drug development. Scientists are investigating its ability to modulate biological pathways, which could lead to new treatments.
  • Research Opportunities: Given its complex structure, this compound represents an excellent opportunity for cheminformatics and structure-activity relationship studies, allowing researchers to optimize its efficacy and selectivity.
  • Literature Insights: As with many compounds in medicinal chemistry, literature on 2-(1-piperidylsulfanyl)-1,3-benzothiazole continues to grow, with numerous studies published that explore its properties and activities. "The pursuit of new chemical entities is key in combating emerging diseases," one researcher noted.

Overall, 2-(1-piperidylsulfanyl)-1,3-benzothiazole stands out as an exciting compound with numerous possibilities for further research and application in health sciences. Its unique structural features and potential for impactful pharmacological activities make it a focal point for scientists and researchers alike.

Synonyms
2-(Piperidinothio)benzothiazole
BENZOTHIAZOLE, 2-(PIPERIDINOTHIO)-
Benzothiazole, 2-(1-piperidinylthio)-
NSC 203009
Piperidine, 1-(2-benzothiazolylthio)-
BRN 0177529
02EEJ0WP97
NSC-203009
UNII-02EEJ0WP97
DTXSID00181287
4-27-00-01869 (Beilstein Handbook Reference)
2-(1-PIPERIDINYLTHIO)BENZOTHIAZOLE
N-PIPERIDYL-2-BENZOTHIAZOLESULFENAMIDE
2-BENZOTHIAZOLESULFENIC ACID PIPERIDIDE
BENZOTHIAZOLE, 2-(1-PIPERIDYLMERCAPTO)-
PIPERIDINE, 1-(2-BENZOTHIAZOLYLMERCAPTO)-
RefChem:84873
DTXCID10103778
Benzothiazole, 2-(1-piperidinylthio)-(9CI)
Piperidine, 1-(2-benzothiazolylthio)-(9CI)
26773-65-9
NSC203009
benzothiazole,2-(1-piperidinylthio)-
2-piperidylthiobenzothiazole
SCHEMBL11545638
AKOS024356477
WLN: T56 BN DSJ CS- AT6NTJ
DS-007229
ST50984332