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Budesonide

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Identification
Molecular formula
C25H34O6
CAS number
51333-22-3
IUPAC name
[2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 2,2-dimethylpropanoate
State
State
At room temperature, Budesonide is in a solid state, specifically a crystalline powder.
Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
430.53g/mol
Molar mass
430.5330g/mol
Density
1.2500g/cm3
Appearence

Budesonide appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl 2,2-dimethylpropanoate

The solubility of the compound 2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl 2,2-dimethylpropanoate is a fascinating subject due to its intricate structure. Understanding the solubility characteristics of this complex molecule involves considering various factors:

  • Polarity: The presence of multiple oxo (carbonyl) groups often enhances the polarity of organic compounds, which may improve their solubility in polar solvents.
  • Hydrophobic Regions: The dodecahydrocyclopenta[a]phenanthrene core contributes a significant hydrophobic portion, potentially reducing solubility in water but increasing solubility in hydrophobic organic solvents.
  • Alkyl Chains: The 2,2-dimethylpropanoate moiety may provide some hydrophilic character, which can affect solubility patterns in various solvent systems.
  • Temperature Dependence: Like many organic compounds, the solubility can vary significantly with temperature; higher temperatures often enhance solubility.

In summary, the solubility of this compound is likely to be influenced by its balance of hydrophobic and hydrophilic features, leading to potential solubility in organic solvents while posing challenges for aqueous solubility. Ultimately, empirical testing is often the most reliable method to determine its solubility under specific conditions. As a general rule, "the solubility of a substance is often dictated by the saying: 'like dissolves like'." This principle is fundamental in predicting solubility behaviors across varying solvent systems.

Interesting facts

Interesting Facts about 2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl 2,2-dimethylpropanoate

This compound belongs to a fascinating class of organic substances known for their complex structures and potential applications in various fields. Here are some intriguing aspects to consider:

  • Structural Complexity: The extensive structure of this compound features a combination of a dodecahydrocyclopenta[a]phenanthren backbone and an oxo-ethyl moiety, showcasing the intricate architecture often found in natural products.
  • Functional Groups: The presence of oxo groups signifies potential reactivity, making this compound an interesting subject for studies on reactivity and synthesis, particularly in terms of how these functional groups can affect the compound's behavior in chemical reactions.
  • Applications: Compounds with similar structural motifs have been researched for their biological activities, including anti-inflammatory and anticancer properties. This compound may also pave the way for novel therapeutic agents.
  • Natural Derivatives: The structural components suggest that it could be related to steroidal frameworks, which are known for their significance in biological systems, particularly in hormonal regulation.
  • Chemical Synthesis: The synthesis of such complex molecules is a testament to advancements in organic chemistry techniques. This compound could serve as a milestone for synthetic chemists in exploring novel pathways for creating intricate organic structures.

This compound exemplifies the rich tapestry of organic chemistry and underscores the importance of continued research in understanding and utilizing complex molecules for innovative applications in medicine and materials science. As physicist Niels Bohr once said, "An expert is a man who has made all the mistakes which can be made in a very narrow field." Each discovery related to compounds like this helps pave new pathways in scientific knowledge!

Synonyms
Doc Pivalate
NCGC00159355-02
Oprea1_314142
CHEMBL1401691
DTXSID30859543
NSC95278
AKOS001581616
AKOS021600016
DB-056466
SR-01000883937
Pregn-4-ene-3, 21-(2,2-dimethyl-1-oxopropoxy)-
SR-01000883937-1
2-{9A,11A-DIMETHYL-7-OXO-1H,2H,3H,3AH,3BH,4H,5H,7H,8H,9H,9AH,9BH,10H,11H,11AH-CYCLOPENTA[A]PHENANTHREN-1-YL}-2-OXOETHYL 2,2-DIMETHYLPROPANOATE