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Dexamethasone acetate

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Identification
Molecular formula
C24H31FO6
CAS number
1177-87-3
IUPAC name
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] acetate
State
State

At room temperature, dexamethasone acetate is in a solid state.

Melting point (Celsius)
262.00
Melting point (Kelvin)
535.00
Boiling point (Celsius)
563.90
Boiling point (Kelvin)
837.00
General information
Molecular weight
434.50g/mol
Molar mass
434.4970g/mol
Density
1.3000g/cm3
Appearence

Dexamethasone acetate is typically a white or almost white crystalline powder. It is practically odorless.

Comment on solubility

Solubility of the Compound

The solubility of [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] acetate, with the chemical formula C24H31FO6, can be influenced by several factors. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups in the compound suggests polarity, which typically enhances solubility in polar solvents like water.
  • Hydrophobic Regions: The compound also contains hydrophobic regions due to its large cyclopenta[a]phenanthrene structure, which may limit its solubility in aqueous environments.
  • Solvent Type: This compound is likely to exhibit better solubility in organic solvents such as ethanol or methanol where both polar and non-polar interactions can occur.
  • Temperature Effects: Generally, increased temperature can lead to increased solubility for many compounds as it allows for greater molecular motion.

As a result, the overall solubility of this compound is a balancing act between its hydrophilic and hydrophobic characteristics. Experimentation is necessary to determine exact solubility values in various solvents, but it is reasonable to expect varied solubility behavior across different environments. To sum up, understanding solubility is vital for applications such as drug formulation, where bioavailability can be significantly influenced by how well a compound dissolves in physiological conditions.

Interesting facts

Interesting Facts about 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl acetate

This fascinating compound belongs to a class of steroids, highlighting the intricate nature of organic chemistry. Here are some captivating insights:

  • Biological Significance: Many compounds in this class play critical roles in various biological processes, particularly in human physiology. They can act as hormones, influencing numerous bodily functions.
  • Structural Complexity: The structure of this compound showcases a complex arrangement of rings and functional groups, indicative of its potential reactivity and interaction with biological systems.
  • The Power of Derivatives: The acetate functional group often enhances the compound’s solubility and ability to penetrate biological membranes, making it a common choice in medicinal chemistry.
  • Research Potential: With its unique structure, this compound could be explored for therapeutic applications, particularly in the realm of endocrinology and oncology, where similar compounds have displayed remarkable efficacy.
  • Historical Context: Synthesis and study of steroid-like compounds date back to the early 20th century, paving the way for groundbreaking discoveries in hormonal treatments, such as the development of contraceptives and anti-inflammatory drugs.

The chemical intricacies of this compound not only make it a subject of interest within academic research but also highlight the endless possibilities in drug discovery and development. As researchers delve deeper into its properties and potential applications, we might soon unveil new therapeutic pathways that can benefit human health.

Synonyms
11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate
MLS002637530
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate
2-{1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl}-2-oxoethyl acetate
NCGC00183367-01
CHEMBL1715636
SCHEMBL13026148
ALEXXDVDDISNDU-UHFFFAOYSA-N
CHEBI:230865
HMS2232P13
HMS3373L06
42016-02-4
BBL033683
STL301800
AKOS001582713
AKOS021734921
AC-12502
SMR001317857
VS-12217
NS00077453
EN300-295955
AH-034/06873032
Pregn-4-ene-3,20-dione,11beta,17alpha,21-trihydroxy-,21 acetate
2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate