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Dexamethasone phosphate

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Identification
Molecular formula
C22H30FO8P
CAS number
2392-39-4
IUPAC name
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] phosphate
State
State

At room temperature, dexamethasone phosphate is typically a solid. It is available in various forms for pharmaceutical use, including tablets, injectables, and topical preparations.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
516.42g/mol
Molar mass
516.4180g/mol
Density
1.4200g/cm3
Appearence

The compound appears as a white to off-white crystalline powder. It is odorless and hygroscopic, absorbing moisture from the air. It is typically used in its hydrated form for pharmaceutical applications.

Comment on solubility

Solubility of 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl phosphate

The solubility of the compound with the formula C22H30FO8P can provide significant insights into its potential applications and behavior in various environments. Understanding solubility is crucial for numerous fields, such as pharmacology, environmental science, and chemical engineering.

Factors Influencing Solubility

Several factors affect the solubility of this compound:

  • Molecular Structure: The presence of hydroxyl groups (-OH) enhances solubility by enabling hydrogen bonding with solvents.
  • Polarity: The phosphate group tends to increase polarity, making the compound more soluble in polar solvents like water.
  • Temperature: Solubility can increase with temperature, promoting more effective interactions between the solvent and solute.

General Solubility Characteristics

Typically, compounds similar in nature have exhibited the following solubility characteristics:

  1. Soluble in polar solvents such as water and alcohols.
  2. Poorly soluble or insoluble in nonpolar solvents like hexane.

In conclusion, while precise solubility data for this compound may vary depending on experimental conditions, it is likely to display significant solubility in polar environments. Therefore, understanding its solubility is key to predicting its behavior and interactions in various scientific applications.

Interesting facts

Exploring the Compound: 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl phosphate

This fascinating compound is a complex organic molecule that highlights the intricate nature of chemical structures and their potential applications in various fields.

Key Features

  • Structure Complexity: The compound boasts a unique fused ring system, which is a hallmark of many biologically active molecules. This complexity may contribute to its unique reactivity and binding properties with biological targets.
  • Potential Biological Activity: Given its structural similarity to steroid derivatives, this compound could have interesting interactions within biological systems, possibly influencing hormone levels or activity.
  • Phosphate Group Influence: The inclusion of a phosphate group suggests the compound may participate in biochemical pathways, possibly acting as a signaling molecule or playing a role in cellular processes.
  • Research Interest: Researchers may find this compound appealing for drug development, especially in the areas of endocrine-related therapies or biochemical signaling.

Scientific Perspective

As we dive deeper into organic synthesis and medicinal chemistry, compounds like this one illuminate the pathways through which complex natural products can lead to significant pharmacological advancements. As one chemist eloquently stated, “The beauty of chemistry lies in its ability to create molecules that can change lives.” This compound encapsulates that beauty, urging scientists to explore its full potential.


Through thorough research and analytical methods, the understanding of this compound's properties can pave the way for innovative approaches in treating various illnesses, showcasing the undeniable link between chemistry and health.