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Betamethasone Valerate

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Identification
Molecular formula
C27H37FO6
CAS number
2152-44-5
IUPAC name
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 3,3-dimethylbutanoate
State
State

At room temperature, Betamethasone valerate is generally available as a solid in the form of a white to creamy semi-opaque crystalline powder. In pharmaceutical preparations, it is often found in liquid or semi-solid states such as creams, ointments, or lotions.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
476.58g/mol
Molar mass
476.5840g/mol
Density
1.1300g/cm3
Appearence

Betamethasone valerate appears as a white to creamy semi-opaque crystalline powder. It may also be available in cream, ointment, or lotion form as a medication.

Comment on solubility

Solubility of [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 3,3-dimethylbutanoate

The solubility of the compound C27H37FO6 can vary significantly based on several factors, including the solvent used and the compound's structural characteristics. Generally speaking, the solubility can be considered under the following categories:

  • Polarity: This compound features various functional groups, such as hydroxyl groups, which typically enhance solubility in polar solvents like water. However, the presence of hydrophobic hydrocarbon chains may limit its solubility in highly polar solvents.
  • Temperature: Increasing temperature usually increases the solubility of organic compounds. Therefore, higher temperatures might improve the solubility of C27H37FO6 in organic solvents.
  • pH Levels: The solubility can also be influenced by the pH of the solution, especially given the presence of functional groups that may ionize, thereby impacting solubility in aqueous environments.
  • Solvent Type: The choice of solvent plays a crucial role. The compound is likely more soluble in organic solvents such as ethanol or methanol compared to water, due to its lipophilicity.

In summary, while C27H37FO6 may show variable solubility depending on external conditions, understanding its solvent interactions helps in predicting its behavior in different mediums. As with many organic compounds, effective solubility testing in specific solvents is essential to obtain reliable data.

Interesting facts

Interesting Facts about 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl 3,3-dimethylbutanoate

This compound represents a fascinating intersection of organic chemistry and pharmacology. It is part of the class of compounds known as steroid derivatives, which can have significant biological activities. Below are some intriguing aspects of this compound:

  • Mechanism of Action: Compounds like this one often interact with hormonal systems, potentially influencing processes such as inflammation, metabolism, and growth.
  • Synthetic Pathways: The synthesis of such complex molecules is a testament to the advancements in organic synthesis techniques, including the use of protecting groups and selective functionalization strategies.
  • Natural Analogues: This compound shares structural similarities with naturally occurring hormones, such as testosterone and cortisol, which play crucial roles in the human body.
  • Research Significance: The exploration of derivatives like this one is vital in drug development, particularly in designing therapies for conditions that require hormonal modulation.
  • Potential Applications: Its potential role in medicinal chemistry makes it an essential subject for ongoing research into cardiovascular disease, cancer therapy, and endocrine-disruptor studies.

In summary, 2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl 3,3-dimethylbutanoate encapsulates a multitude of possibilities, from its sophisticated structural characteristics to its potential therapeutic applications. Understanding such compounds enhances our grasp of biochemistry and opens new avenues for medical advancements.

Synonyms
Prednisolone_Tebutate