Skip to main content

Fluticasone propionate

ADVERTISEMENT
Identification
Molecular formula
C25H31F3O5S
CAS number
80474-14-2
IUPAC name
[2-(12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl)-2-oxo-ethyl] 3-benzamido-2-methyl-propanoate
State
State

Fluticasone propionate is typically a solid at room temperature. In pharmaceutical applications, it is often formulated into creams or inhalable products.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
500.57g/mol
Molar mass
500.5730g/mol
Density
1.2206g/cm3
Appearence

Fluticasone propionate is a white powder. It is often used in the formulation of creams, inhalers, and nasal sprays, where its appearance may vary based on the product form.

Comment on solubility

Solubility of [2-(12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl)-2-oxo-ethyl] 3-benzamido-2-methyl-propanoate

The solubility of [2-(12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl)-2-oxo-ethyl] 3-benzamido-2-methyl-propanoate, with the chemical formula C25H31F3O5S, presents interesting characteristics to consider:

  • Potential Solubility in Organic Solvents: Given its complex structure and presence of various functional groups, this compound might exhibit better solubility in non-polar to moderately polar organic solvents.
  • Hydrophobic Character: The significant hydrocarbon portions suggest a hydrophobic nature, potentially limiting its solubility in water.
  • Hydrophilic Influences: The presence of functional groups such as the hydroxyl (-OH) and carbonyl (C=O) may enhance solubility in polar solvents.
  • Influence of Fluorine: The fluorine atom can introduce unique solubility properties, potentially increasing stability and affecting how the compound interacts with solvents.

In summary, while the exact solubility profile may require further empirical studies, it is likely that this compound will show enhanced solubility in specific organic solvents due to its intricate balance of hydrophobic and hydrophilic characteristics. Keep in mind the intricate balance of its molecular structure can lead to varied solubility depending on the solvent environment.

Interesting facts

Exploring 2-(12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl)-2-oxo-ethyl] 3-benzamido-2-methyl-propanoate

The compound identified as 2-(12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl)-2-oxo-ethyl] 3-benzamido-2-methyl-propanoate is a fascinating chemical entity with intriguing characteristics. This compound belongs to a class of chemicals noted for their structural complexity and potential bioactivity, making them objects of interest in both academic research and pharmaceutical development.

Key Features

  • Structural Diversity: This compound features a unique pentacyclic system, which is composed of interconnected rings. Such structures often exhibit diverse biological activities.
  • Fluorine Substitution: The presence of the F atom enhances the stability and lipophilicity of the compound, which can improve its pharmacokinetic properties.
  • Hydroxyl Group: Hydroxyl groups contribute to hydrogen bonding capabilities and can significantly affect the solubility and interaction with biological targets.

The synthesis of such complex compounds often involves multi-step processes that can require advanced methodologies, making them a topic of dedicated study in organic chemistry. Moreover, their potential applications in drug design highlight the importance of understanding how variations in structure can lead to different biological outcomes.

Applications and Implications

  • Pharmaceutical Development: Due to its unique properties, this compound may be explored for therapeutic applications, particularly in fields such as anticancer and antiviral research.
  • Research Interest: Compounds of this nature are pivotal in the study of mechanism-based drug design, where understanding the interaction of the compound with biological molecules is crucial.

As we delve deeper into the chemical intricacies of this compound, it becomes clear that compounds like it not only challenge our understanding of bonding and reactivity but also open doors to innovative medical therapies. Scientists continuously seek to unravel the mysteries of such compounds, emphasizing the importance of multidisciplinary approaches in modern chemical research.

Synonyms
DTXSID80865578
2-(4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH,8H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethyl 3-benzamido-2-methylpropanoate