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Safrole hydroxamide

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Identification
Molecular formula
C9H9NO3
CAS number
2150-47-2
IUPAC name
2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine
State
State
This compound is typically found in solid form at room temperature.
Melting point (Celsius)
184.50
Melting point (Kelvin)
457.65
Boiling point (Celsius)
319.80
Boiling point (Kelvin)
592.95
General information
Molecular weight
181.18g/mol
Molar mass
181.1830g/mol
Density
1.2950g/cm3
Appearence

2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine appears as a solid compound at room temperature. It is often white or off-white in appearance.

Comment on solubility

Solubility of 2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine

The solubility of 2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine can be considered under various conditions and is influenced by several factors:

  • Polarity: Given the presence of the hydroxy group and the complex benzodioxole ring, this compound exhibits a degree of polarity, which can enhance its solubility in polar solvents.
  • Solvent Interaction: It is generally soluble in water and other polar solvents due to hydrogen bonding capabilities, while its solubility in non-polar solvents is likely limited.
  • Temperature Effects: As with many compounds, solubility may increase with temperature, making it essential to consider the conditions under which solubility is measured.
  • Concentration Dependency: The solubility can vary significantly with concentration, particularly near saturation levels.

In conclusion, although 2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine displays good solubility in polar environments, a detailed quantitative assessment in various solvents will provide a clearer picture of its behavior in practical applications.

Interesting facts

Interesting Facts about 2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine

2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine is a fascinating compound that showcases the beauty of organic synthesis and the intricate world of functional groups. Here are some remarkable facts about this compound:

  • Structural Features: The unique 1,3-benzodioxole moiety contributes to its distinctive properties. This structural configuration is known for its ability to engage in various chemical reactions.
  • Biological Significance: Compounds like this one often serve as intermediates in the development of pharmaceuticals. Researchers are continuously exploring their potential therapeutic applications, particularly in the realm of neurology and psychiatry.
  • Chemical Reactivity: The presence of the **hydroxyl** group makes this compound a potential candidate for nucleophilic substitutions, enabling further functionalization which can lead to new derivatives with varying biological activities.
  • Research and Application: Given its complexity, this compound has been the subject of various studies aimed at understanding its interactions within biological systems and how those interactions can be harnessed in medicinal chemistry.

In conclusion, 2-(1,3-benzodioxol-5-yl)-2-hydroxy-acetamidine exemplifies how small modifications to molecular structures can lead to significant changes in behavior and utility. As science continues to unravel the intricacies of such compounds, the future holds exciting possibilities for their application in human health and industry.

Synonyms
Olmidine
22693-65-8
Dl-olmidine
3,4-(Methylenedioxy)mandelamidine
0T3B934Y1M
alpha-Hydroxy-1,3-benzodioxole-5-ethanimidamide
DL-2-(3,4-methylenedioxyphenyl)-2-hydroxyacetamidine
RefChem:928185
Olmidina
Olmidine, (+)-
Olmidine, (-)-
CWA7D4VAX8
2-(1,3-benzodioxol-5-yl)-2-hydroxyethanimidamide
2-(2H-1,3-benzodioxol-5-yl)-2-hydroxyethanimidamide
6X082H783C
31105-14-3
Olimidine
LL 1418
46319-96-4
788094-87-1
Olmidinum
dl-Mandelamidine
UNII-0T3B934Y1M
Olmidine [INN:DCF]
Olmidinum [INN-Latin]
Olmidina [INN-Spanish]
3,4-Methylendioxy)mandelamine
2-(1,3-Benzodioxol-5-yl)glycolamidin
OLMIDINE [INN]
UNII-CWA7D4VAX8
2-(1,3-dioxaindan-5-yl)-2-hydroxyethanimidamide
1,3-Benzodioxole-5-ethanimidamide, .alpha.-hydroxy-
orb1701846
SCHEMBL1818320
CHEMBL2104702
UNII-6X082H783C
DTXSID90865064
AKOS006273694
HY-105718
NS00121094
EN300-262064
(2H-1,3-Benzodioxol-5-yl)(hydroxy)ethanimidamide
Q27237220
MANDELAMIDINE, 3,4-(METHYLENEDIOXY)-, (+/-)-
1,3-Benzodioxole-5-ethanimidamide, alpha-hydroxy-, (+)-
1,3-Benzodioxole-5-ethanimidamide, alpha-hydroxy-, (-)-
1,3-BENZODIOXOLE-5-ETHANIMIDAMIDE, .ALPHA.-HYDROXY-, (+)-
1,3-BENZODIOXOLE-5-ETHANIMIDAMIDE, .ALPHA.-HYDROXY-, (-)-
1,3-BENZODIOXOLE-5-ETHANIMIDAMIDE, .ALPHA.-HYDROXY-, (+/-)-