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Methylenedioxyphenethylamine (MDPEA)

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Identification
Molecular formula
C10H13NO2
CAS number
20334-69-4
IUPAC name
2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine
State
State

At room temperature, Methylenedioxyphenethylamine (MDPEA) is typically found in a crystalline solid state, although it may also appear as a liquid under certain conditions depending on synthesis and purity.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
165.19g/mol
Molar mass
165.1850g/mol
Density
1.1510g/cm3
Appearence

Methylenedioxyphenethylamine (MDPEA) appears as a colorless to light yellow liquid or, in some formulations, a crystalline powder. It is a compound of interest primarily for research purposes.

Comment on solubility

Solubility of 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine

The compound 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine, a member of the substituted amine family, exhibits notable solubility characteristics influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of both aromatic groups and nitrogen functionality contributes to the compound's polar nature, enhancing its solubility in polar solvents.
  • Solvent Compatibility: This compound demonstrates good solubility in water, methanol, and ethanol, typically due to hydrogen bonding possibilities.
  • Effects of Temperature: As with many organic compounds, increased temperature can further improve solubility rates, suggesting that higher temperatures might facilitate greater dissolution.
  • Influence of pH: The solubility may be affected by the pH of the solution, as the amine group can become protonated in acidic conditions, increasing solubility in such environments.

In summary, the solubility of 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine is influenced by its polar character and the ability to interact with various solvent systems, making it an interesting compound for further exploration in different chemical environments.

Interesting facts

Interesting Facts about 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine

The compound 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine, commonly known within the scientific community for its intriguing structural components, offers a wealth of insights into chemical properties, synthesis methods, and potential applications.

1. Structural Characteristics

  • Core Structure: This compound features a benzodioxole moiety, which adds significant stability and aromatic characteristics.
  • Alkyl Substitution: The N-methyl group contributes not only to the compound's basicity but also to its potential reactivity with various electrophiles.

2. Biological Relevance

This compound is often studied in the context of pharmacology due to its structural similarity to several psychoactive substances. It is of notable interest because it may affect neurotransmitter systems in the brain:

  • Dopamine: It has been speculated that derivatives of this compound might interact with dopamine receptors.
  • Serotonin: Studies suggest possible engagement with serotonin pathways, which could imply implications for mood and cognition.

3. Synthesis Techniques

Synthesizing 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine often involves:

  • The condensation of benzodioxole with appropriate amines.
  • Use of protective groups to ensure selectivity in reactions.
  • Employing modern techniques such as microwave-assisted synthesis to improve yields and reduce reaction times.

4. Potential Applications

Due to its unique molecular structure and biological interaction potential, the compound could pave the way for industrial and medicinal uses:

  • Pharmaceutical Development: It may serve as a lead compound in the search for new psychotropic medications.
  • Research Applications: It can be utilized in studies aimed at understanding the mechanisms of action of neurotransmitters.

In summary, the compound 2-(1,3-benzodioxol-5-yl)-N-methyl-ethanamine represents a fascinating subject of study in chemistry and pharmacology, with its unique properties, potential applications, and methodologies reflecting the intricate links between structure and function in chemical compounds. As noted by scientists, "Understanding these compounds is crucial for the advancement of both theoretical and applied chemistry."

Synonyms
Homarylamine
451-77-4
Homarilamina
Homarylamine [INN]
Homarylaminum
Mdmpea
N-methylhomopiperonylamine
Homarylaminum [INN-Latin]
Homarilamina [INN-Spanish]
Mk-71
6FJ4B5B368
N-Methyl-1,3-benzodioxol-5-ethylamin
N-Methyl-3,4-methylenedioxyphenethylamine
HOMARYLAMINE [NFLIS-DRUG]
DTXSID90196385
[2-(1,3-dioxaindan-5-yl)ethyl](methyl)amine
Homarylaminum (INN-Latin)
Homarilamina (INN-Spanish)
HOMARYLAMINE (NFLIS-DRUG)
(2-(1,3-dioxaindan-5-yl)ethyl)(methyl)amine
DTXCID00118876
973-580-4
5-[2-(Methylamino)ethyl]-1,3-benzodioxole
2-(1,3-benzodioxol-5-yl)-N-methylethanamine
[2-(2H-1,3-benzodioxol-5-yl)ethyl](methyl)amine
UNII-6FJ4B5B368
1,3-Benzodioxole-5-ethanamine, N-methyl-
N-Methylhomopiperonylamin
SCHEMBL1237889
CHEMBL2104353
CHEBI:134816
OPJOMVMFYOUDPK-UHFFFAOYSA-N
AC6162
MFCD00868863
AKOS006240982
SY026811
DB-229290
CS-0452617
NS00067972
EN300-386288
Q6823985
2-(Benzo[d][1,3]dioxol-5-yl)-N-methylethan-1-amine
F1911-1816