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2-(2-Hydroxyphenyl)benzoxazole

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Identification
Molecular formula
C13H9NO2
CAS number
1137-42-4
IUPAC name
2-(1,3-benzoxazol-2-yl)phenol
State
State

At room temperature, 2-(2-Hydroxyphenyl)benzoxazole is in a solid state, appearing as a crystalline powder. It is stable under standard conditions and does not undergo significant changes unless exposed to higher temperatures.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.15
General information
Molecular weight
211.22g/mol
Molar mass
211.2210g/mol
Density
1.3550g/cm3
Appearence

2-(2-Hydroxyphenyl)benzoxazole typically appears as a pale yellow crystalline powder. The powder form consists of fine crystals, which contribute to its bulk density and texture. It may appear somewhat translucent in larger crystals and opaque in fine powder form. Depending on purity, the material can also have a sheen or gloss.

Comment on solubility

Solubility of 2-(1,3-benzoxazol-2-yl)phenol

The compound 2-(1,3-benzoxazol-2-yl)phenol exhibits intriguing solubility characteristics due to its organic structure and functional groups. Understanding its solubility is key for various applications and research. Here are some important aspects to consider:

  • Polar Nature: The presence of hydroxyl groups (–OH) contributes to the polar characteristics of the compound, which generally enhances solubility in polar solvents such as water.
  • Aromatic Systems: The benzoxazole and phenol moieties give rise to hydrophobic interactions, potentially reducing solubility in non-polar solvents.
  • Solvent Compatibility: Typically soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), while demonstrating limited solubility in aliphatic hydrocarbons.
  • pH Sensitivity: Solubility can vary with pH; increased solubility is often observed in alkaline conditions due to deprotonation of the hydroxyl group.

In summary, the solubility of 2-(1,3-benzoxazol-2-yl)phenol is influenced by its unique structural features, making it an interesting subject for further study. As expressed in various studies, "solubility is a critical property that governs the behavior of chemical compounds in solution," highlighting its importance in both practical applications and scientific research.

Interesting facts

Interesting Facts about 2-(1,3-benzoxazol-2-yl)phenol

2-(1,3-benzoxazol-2-yl)phenol, often referred to in scientific discussions as a versatile compound, presents numerous points of interest for both researchers and students alike. Here are some notable aspects of this intriguing compound:

  • Structural Characterization: This compound incorporates both a phenolic and a benzoxazole moiety, which contributes to its unique chemical properties and reactivity.
  • Biological Significance: Studies have suggested that derivatives of this compound exhibit various biological activities, including antimicrobial and antioxidant properties, making it a potential candidate in medicinal chemistry.
  • Polymer Chemistry: Its phenolic structure allows for incorporation into polymer matrices, which enhances thermal stability and can improve mechanical properties in composite materials.
  • Fluorescent Properties: Some research indicates that compounds like 2-(1,3-benzoxazol-2-yl)phenol can demonstrate fluorescence, leading to applications in organic light-emitting diodes (OLEDs) and fluorescent probes.
  • Research Potential: Its multifaceted functionalities provide a great platform for further exploration in fields such as materials science and bioengineering.

As you study 2-(1,3-benzoxazol-2-yl)phenol, consider its unique combination of structural characteristics and applications. The insights gained may lay the groundwork for innovative solutions in various scientific domains. As a wise chemist once said, "The essence of chemistry lies in the connections formed at the molecular level."

Synonyms
835-64-3
2-(2-HYDROXYPHENYL)BENZOXAZOLE
2-(o-Hydroxyphenyl)benzoxazole
Phenol, 2-(2-benzoxazolyl)-
2-Benzoxazol-2-ylphenol
2-(2-benzoxazolyl)phenol
Phenol, o-2-benzoxazolyl-
USAF EK-6754
NSC 5423
CCRIS 7875
NSC 403545
RG8GW8KSU5
EINECS 212-642-0
BRN 0173017
NSC-5423
NSC-403545
DTXSID4061200
4-27-00-02080 (Beilstein Handbook Reference)
DTXCID3048360
Phenol, o-2-benzoxazolyl-(8CI)
212-642-0
2-(benzo[d]oxazol-2-yl)phenol
2-(1,3-Benzoxazol-2-yl)phenol
MFCD00005767
o-(2-Benzoxazolyl)phenol
2-(2'-hydroxyphenyl)benzoxazole
WLN: T56 BN DOJ CR BQ
2-Benzooxazol-2-yl-phenol
o-2-benzoxazolylphenol
Enamine_005881
UNII-RG8GW8KSU5
Oprea1_077278
SCHEMBL56592
2-(O-Hydroxyphenyl)benzoxazol
CHEMBL1650631
SCHEMBL11984913
2-(O-Hydroxy phenyl)benzoxazole
NSC5423
2-(2'-hydroxylphenyl)benzoxazole
CHEBI:180630
HMS1410L07
ALBB-014152
2-(ortho-Hydroxyphenyl)-benzoxazole
NSC403545
STK731652
AKOS000669321
2-(2-Hydroxyphenyl)-1,3-benzoxazole
2-(2-Hydroxyphenyl)benzoxazole, 98%
CCG-103213
CS-W015057
IDI1_008116
AS-59719
SY077623
DB-056723
EU-0033400
H0291
NS00042086
D71022
SR-01000389308
SR-01000389308-1
BRD-K11826754-001-02-4
Z56756575