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Cortisone acetate

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Identification
Molecular formula
C23H30O6
CAS number
50-04-4
IUPAC name
[2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] acetate
State
State

Cortisone acetate is a solid at room temperature.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
402.50g/mol
Molar mass
402.4970g/mol
Density
1.3000g/cm3
Appearence

Cortisone acetate generally appears as a white or almost white crystalline powder. It is odorless and stable under normal temperatures and pressures.

Comment on solubility

Solubility of [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] acetate: C23H30O6

The solubility of this compound, characterized by its complex molecular structure, can be influenced by several factors. Understanding these factors is crucial for its practical applications. Here’s what to consider:

  • Polarity: The presence of multiple functional groups, including hydroxyl (-OH) and ester groups, suggests that the compound may exhibit varying degrees of polarity, affecting its solubilization in different solvents.
  • Solvent Compatibility: Typically, organic compounds with similar structures tend to be soluble in organic solvents such as dichloromethane, ethanol, or acetone. “Like dissolves like” is a common rule that facilitates solubility predictions.
  • Temperature Dependence: Increasing temperature often enhances solubility, particularly for solid compounds. This principle can be applied during experimental dissolutions.
  • pH Levels: As this compound contains hydroxyl groups, its solubility may change with varying pH levels, especially in aqueous solutions.

In conclusion, while the solubility of [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] acetate can be inferred based on its structural characteristics, empirical testing is essential for precise determination. Factors such as polarity, solvent nature, temperature, and pH will play significant roles in achieving optimal solubility conditions.

Interesting facts

Interesting Facts about 2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl acetate

This compound represents a fascinating example of a steroid derivative, significant due to its structural complexity and potential biological implications. Here are some engaging insights about this unique chemical:

  • Steroid Backbone: The compound features a steroid nucleus, which is critical for many biological hormones in the body, such as testosterone and estrogen. Its intricate structure suggests potential interactions with biological systems.
  • Hydroxyl and Carbonyl Functional Groups: The presence of hydroxyl (-OH) and carbonyl (C=O) groups enhances its reactivity, making it a candidate for further functionalization in synthetic chemistry, which can lead to new therapeutic agents.
  • Natural Sources: Compounds like this one can be derived from natural products, particularly from plants and fungi, known for producing unique metabolites that have promising pharmacological activities.
  • Potential Biological Activity: The complexity of this compound raises the question of its biological activity. Many steroid derivatives are known for their anti-inflammatory, anti-cancer, and hormone-regulating properties, sparking interest in its potential applications in medicine.
  • Structure-Function Relationship: The architecture of the compound, including dimethyl and dioxo groups, may significantly impact its biological function, lending it potential as a lead compound in drug discovery.
  • Research Trends: Chemical compounds with similar structures are at the forefront of research in medicinal chemistry, where scientists strive to understand their mechanisms of action and find innovative applications.

As research in chemistry and pharmacology continues to evolve, compounds like this one exemplify the bridge between synthetic ingenuity and natural product chemistry. Given its structural characteristics, 2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl acetate stands as a testament to the rich potential of complex molecules in understanding and treating human health.

Synonyms
17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate
2-{1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl}-2-oxoethyl acetate
ITRJWOMZKQRYTA-UHFFFAOYSA-N
ALBB-033476
AKOS040766471
LS-12715
EN300-296076
4-Pregnene-3,11,20-trione, 17alpha,21-dihydroxy-, 21-acetate