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Fluocinolone acetonide

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Identification
Molecular formula
C24H30F2O6
CAS number
67-73-2
IUPAC name
[2-(19-fluoro-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-8-yl)-2-oxo-ethyl] acetate
State
State

Fluocinolone acetonide is in a solid state at room temperature. It is stable under normal conditions but may require specific storage conditions to maintain its efficacy and prevent degradation.

Melting point (Celsius)
270.00
Melting point (Kelvin)
543.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
452.50g/mol
Molar mass
452.4960g/mol
Density
1.3600g/cm3
Appearence

Fluocinolone acetonide appears as a white to off-white crystalline powder. It is often finely divided and has no significant odor.

Comment on solubility

Solubility Properties of [2-(19-fluoro-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-8-yl)-2-oxo-ethyl] acetate

The solubility of this compound, with its complex structure, can be influenced by a variety of factors. Here are some key points to consider:

  • Polarity: The presence of functional groups such as esters and ketones suggests that polarity may play a significant role in its solubility.
  • Solvents: It may be more soluble in polar solvents like methanol or ethanol compared to non-polar solvents, due to potential interactions between the compound's functional groups and the solvent molecules.
  • Temperature Influence: Solubility can be temperature-dependent; typically, as temperature increases, so does solubility, particularly for organic compounds.
  • Hydrogen Bonding: The ability for the molecule to engage in hydrogen bonding with solvents could enhance its solubility in certain conditions.
  • Crystal Structure: A more crystalline form of the compound may lead to lower solubility, whereas an amorphous state generally enhances solubility.

In conclusion, while the exact solubility of [2-(19-fluoro-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-8-yl)-2-oxo-ethyl] acetate can vary, it is important to consider the influence of molecular structure and environmental conditions in predicting its behavior in different solvents.

Interesting facts

Interesting Facts about 2-(19-Fluoro-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-8-yl)-2-oxo-ethyl Acetate

This fascinating compound is an example of a complex organic molecule that showcases the beauty of chemical diversity. Here are some intriguing points about it:

  • Structural Complexity: The compound features a unique pentacyclic structure, indicating a high degree of molecular intricacy. It consists of multiple fused rings which contribute to its stability and reactivity.
  • Fluorination Impact: The presence of a fluorine atom in the structure not only enhances the lipophilicity of the compound but also potentially affects its biological activity. This modification is a common strategy in medicinal chemistry to improve pharmacological properties.
  • Applications in Medicine: Compounds with similar structural motifs are often explored for their therapeutic potentials. They are typically evaluated for roles in drug development, especially in combating various diseases.
  • Natural Analogues: Many complex organic molecules resemble natural products, which can provide leads for drug discovery. This compound could be related to natural substances that exhibit antibacterial or antiviral properties.
  • Synthetic Challenges: The synthesis of such intricate compounds poses considerable challenges and often requires multiple steps, specific reaction conditions, and careful planning to obtain the desired product without unwanted by-products.

As chemists delve deeper into the study of compounds like this, they venture into uncharted territories of molecular transformations and functionalization, pushing the boundaries of what is possible in the field of organic chemistry. Exploring these compounds not only enriches our understanding of chemistry but can also lead to breakthroughs in therapeutic applications.

"In complexity, we find potential." - Anonymous

Synonyms
NS00100949