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2-(1H-benzimidazol-2-yl)phenol

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Identification
Molecular formula
C13H10N2O
CAS number
25556-06-3
IUPAC name
2-(1H-benzimidazol-2-yl)phenol
State
State

At room temperature, 2-(1H-benzimidazol-2-yl)phenol is a solid. This compound typically exists as crystalline powder, with its form and texture possibly affecting handling and measurement.

Melting point (Celsius)
326.00
Melting point (Kelvin)
599.00
Boiling point (Celsius)
523.00
Boiling point (Kelvin)
796.00
General information
Molecular weight
210.23g/mol
Molar mass
210.2270g/mol
Density
1.3580g/cm3
Appearence

2-(1H-benzimidazol-2-yl)phenol typically appears as a crystalline solid and can vary in color, often being off-white or pale yellow in form. The compound is characterized by its benzene and benzimidazole rings, which contribute to its aromaticity.

Comment on solubility

Solubility of 2-(1H-benzimidazol-2-yl)phenol

The solubility of 2-(1H-benzimidazol-2-yl)phenol in various solvents presents interesting characteristics. This compound is generally considered to be:

  • Moderately soluble in organic solvents such as ethanol and methanol.
  • Insoluble in water, which limits its applications in aqueous environments.

It is important to note that the solubility can be influenced by several factors:

  1. Temperature: Increased temperature often leads to enhanced solubility, especially in organic solvents.
  2. pH Level: The ionization of the compound can be affected by the pH, thus modifying its solubility.
  3. Presence of other solutes: The addition of specific salts or complexing agents may either enhance or reduce solubility.

As stated, "Solubility is a dynamic property that alters with the chemical environment," making it essential to consider these factors when working with 2-(1H-benzimidazol-2-yl)phenol in practical applications.

Hence, understanding the solubility profile of this compound is vital for effective utilization in various fields such as pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 2-(1H-benzimidazol-2-yl)phenol

2-(1H-benzimidazol-2-yl)phenol is a fascinating chemical compound that has garnered attention in various fields, particularly in medicinal chemistry and material science. Here are some intriguing aspects of this compound:

  • Biological Significance: This compound exhibits potent biological activities, including antimicrobial, antioxidant, and anticancer properties. Researchers are exploring its potential for developing new therapeutic agents.
  • Pharmacological Applications: The presence of the benzimidazole moiety, known for its diverse pharmacological effects, makes 2-(1H-benzimidazol-2-yl)phenol a promising candidate for drug design and synthesis.
  • Structural Versatility: The structure of 2-(1H-benzimidazol-2-yl)phenol allows for various modifications, which can enhance its efficacy and specificity when targeting different biological pathways.
  • Material Science: Beyond its medicinal properties, this compound is also studied in material science for potential applications in the development of organic light-emitting diodes (OLEDs) and sensors due to its electronic properties.
  • Research on Mechanisms: Ongoing studies focus on understanding the specific mechanisms by which this compound exerts its biological effects, which may reveal new pathways for treatment and drug development.

As stated by leading researchers, "The exploration of novel compounds like 2-(1H-benzimidazol-2-yl)phenol represents the frontier of modern chemistry, bridging the gap between synthetic development and practical application in health and technology."

This compound is an excellent example of how a single structural change can lead to a wide array of applications across multiple fields, highlighting the interconnected nature of chemistry and its impact on society.

Synonyms
2963-66-8
Phenol, 2-(1H-benzimidazol-2-yl)-
2-(1H-Benzimidazol-2-yl)phenol
2-(o-Hydroxyphenyl)benzimidazole
2-(2-Hydroxyphenyl)benzimidazole
2-(2-Benzimidazolyl)phenol
2-(2'-Hydroxyphenyl)benzimidazole
Phenol, o-2-benzimidazolyl-
2-(2'-Oxyphenyl)benzimidazole
NSC 32819
DTXSID7062746
DTXCID2038029
xwxmgtihbyftie-uhfffaoysa-n
2-(1H-benzo[d]imidazol-2-yl)phenol
2-(2-Hydroxyphenyl)-1H-benzimidazole
2-(1H-1,3-benzodiazol-2-yl)phenol
2-(1H-Benzoimidazol-2-yl)-phenol
2-(2-Hydroxyphenyl)1H-benzimidazole
2-(2-Hydroxyphenyl)-1H-benzoimidazole
MFCD00022668
CHEMBL203360
2-(2 inverted exclamation marka-Hydroxyphenyl)benzimidazole
2-(1H-Benzimidazole-2-yl)phenol
2-(1H-Benzimidazole-Z-yl)phenol
NSC32819
PHENOL,2-(1H-BENZIMIDAZOL-2-YL)-
ChemDiv1_018687
Cambridge id 5310716
Oprea1_407005
Oprea1_643153
DivK1c_003471
SCHEMBL461968
HMS640B09
6-(1,3-dihydrobenzimidazol-2-ylidene)cyclohexa-2,4-dien-1-one
BDBM50180727
CCG-15084
NSC-32819
STK726803
AKOS000275527
HY-W140203
CDS1_002431
AS-37909
PD158855
DS-022231
CS-0196394
H1736
NS00006336
2-(2-Hydroxyphenyl)-1H-benzimidazole, 95%
SR-01000389041
SR-01000389041-1
Z57115066
F0852-0136