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Histamine

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Identification
Molecular formula
C5H9N3
CAS number
51-45-6
IUPAC name
2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine
State
State

At room temperature, histamine is typically a solid. It is usually handled at room temperature as a crystalline powder, which is the most stable form for most applications, particularly in chemical and pharmaceutical settings.

Melting point (Celsius)
82.00
Melting point (Kelvin)
355.00
Boiling point (Celsius)
202.00
Boiling point (Kelvin)
475.00
General information
Molecular weight
111.16g/mol
Molar mass
111.1550g/mol
Density
1.3000g/cm3
Appearence

Histamine is typically a white crystalline powder. It is colorless and can also appear in a form that resembles fine crystals. It is hygroscopic, meaning it can absorb moisture from the environment, which may affect its texture and appearance.

Comment on solubility

Solubility of 2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine

The solubility of 2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine is an interesting topic due to its unique structure. This compound, containing an imidazole ring, can exhibit distinct solubility characteristics that often depend on various factors such as:

  • Polarity: The presence of polar functional groups in the molecule can enhance its solubility in polar solvents like water.
  • Temperature: Generally, increasing the temperature of the solvent may improve solubility.
  • pH Levels: As an amine, its protonation can affect solubility in acidic or basic environments.
  • Concentration: High concentrations of solute may lead to precipitation, thus limiting solubility.

It is often observed that compounds with imidazole rings tend to show reasonable solubility in aqueous solutions, but this can vary widely based on substituents and environmental conditions. In summary, while 2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine may exhibit decent solubility in polar solvents, experimental evaluation is essential for precise determinations.

Interesting facts

Exploring 2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine

2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine, often referred to in the scientific community as a derivative of imidazole, is an intriguing chemical compound with various applications and characteristics that merit discussion. Here are some insightful aspects about this compound:

  • Biological Significance: This compound features the imidazole ring, which is a crucial component in many biological systems. Imidazole derivatives can often act as biological catalysts and have roles in enzyme activity.
  • Pharmacological Potential: Research has suggested that compounds with imidazole structures may display a variety of pharmacological activities, including anti-inflammatory and antifungal properties. They serve as vital precursors in the synthesis of numerous medications.
  • Synthesis and Versatility: The synthesis of this compound can often be achieved through well-established organic reactions, making it a versatile building block for more complex molecules in medicinal chemistry.
  • Research Applications: This compound can be utilized in various fields of research, including material sciences and pharmaceuticals, showcasing its multifaceted nature.

In summary, 2-(1H-imidazol-5-yl)-N,N-dimethyl-ethanamine stands as a noteworthy compound that exemplifies the intersection of organic chemistry and biological applications. Its diverse potential and exciting properties continue to make it a subject of scientific interest.

Quotable Insight

As one researcher aptly put it, "The beauty of organic compounds lies in their ability to bridge numerous fields of science, with each compound telling a unique story."

Synonyms
N,N-Dimethylhistamine
673-46-1
2-(1H-imidazol-5-yl)-N,N-dimethylethanamine
4-(2-Dimethylaminoethyl)imidazole
SU-416
Na,Na-Dimethylhistamine
[2-(1H-imidazol-4-yl)ethyl]dimethylamine
N(sup alpha),N(sup alpha)-Dimethylhistamine
N',N'-Dimethylhistamine
1H-Imidazole-4-ethanamine, N,N-dimethyl-
132366-08-6
Imidazole, 4-[2-(dimethylamino)ethyl]-
IMIDAZOLE, 4-(2-(DIMETHYLAMINO)ETHYL)-
4-(2-(Dimethylamino)ethyl)-Imidazole
4-[2-(Dimethylamino)ethyl]-Imidazole
Hippospongine?
Dimethylhistamine
N-dimethylhistamine
N(alpha),N(alpha)-dimethylhistamine
CHEMBL12704
GTPL1270
SCHEMBL1239352
DTXSID30986565
Nalpha ,Nalpha -dimethylhistamine
CHEBI:178169
N-alpha,N-alpha-Dimethylhistamine
N-omega,N-omega-Dimethylhistamine
ZJDIMSMQXMWMCF-UHFFFAOYSA-N
N.alpha.,N.alpha.-Dimethylhistamine
N.omega.,N.omega.-Dimethylhistamine
AKOS006349678
N,N-Dimethyl-1H-Imidazole-4-ethanamine
NS00094417
2-(3H-imidazol-4-yl)-N,N-dimethylethanamine
N,N-Dimethyl-1H-imidazole-4-ethanamine, 9CI
EN300-2000952
2-(1H-Imidazol-4-yl)-N,N-dimethylethan-1-amine
2-(1H-Imidazol-5-yl)-N,N-dimethylethan-1-amine
L024080
N-[2-(1H-Imidazol-4-yl)ethyl]-N,N-dimethylamine
N-[2-(1H-Imidazol-4-yl)ethyl]-N,N-dimethylamine #
Q27078073
NLaquo Omegaraquo ,Nlaquo Omegaraquo -dimethylhistamine