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2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide

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Identification
Molecular formula
C13H17N3O
CAS number
54654-29-8
IUPAC name
2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide
State
State

At room temperature, 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide is typically found in a solid state.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
245.30g/mol
Molar mass
245.3010g/mol
Density
1.2983g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide

The solubility of 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide is an intriguing subject, as it behaves in unique ways under different conditions. This compound is known to exhibit:

  • Moderate solubility in polar solvents: Such as water and methanol, facilitating its use in various biochemical applications.
  • Decreased solubility in non-polar solvents: Compounds like hexane or toluene typically do not solubilize this hydrazide effectively.
  • Temperature dependence: Its solubility may increase with temperature, which is a common characteristic for many organic compounds.

In practical terms, the solubility profile of 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide can be summarized as:

  1. Highly soluble in polar solvents.
  2. Poorly soluble in non-polar solvents.
  3. Temperature-sensitive solubility behavior.

As a result, understanding the solubility of this compound is pivotal for its utilization in various applications, such as drug formulation and organic synthesis. “Solubility is not just a property; it's a gateway to innovation in chemical science!

Interesting facts

Exploring 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide

2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide is a fascinating compound that finds its significance primarily in the realms of medicinal chemistry and pharmacology. Here are some intriguing aspects of this chemical:

  • Indole Framework: The compound features an indole ring, a core structure known for its presence in various natural products and pharmaceuticals. The indole moiety often contributes to biological activity, making compounds containing it a topic of great interest in drug discovery.
  • Hydrazide Functional Group: The presence of a hydrazide functional group in this compound is noteworthy. Hydrazides have been identified as potential therapeutic agents with applications ranging from anti-cancer to anti-tubercular activities.
  • Synthetic Utility: This compound may serve as a valuable building block in synthetic chemistry. The acetohydrazide part can undergo further reactions, opening pathways to a variety of new derivatives.
  • Research Focus: Compounds like 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide are continuously being investigated for their pharmacological potential. Studies may reveal unique mechanisms of action, offering insights into their efficacy as therapeutic agents.
  • Structure-Activity Relationship (SAR): This compound provides a platform for SAR studies. By modifying various parts of the molecule, scientists can assess which structural changes lead to enhanced biological activities, thereby refining their drug development efforts.

In summary, 2-(1H-indol-3-yl)-N'-isopropyl-acetohydrazide is not just a simple chemical entity; it represents a point of intersection between synthetic chemistry and medicinal research. As scientists continue to explore its properties and potential applications, this compound could play a pivotal role in the development of new therapeutics.

Synonyms
BRN 0480722
INDOLE-3-ACETIC ACID, 2-ISOPROPYLHYDRAZIDE
N(sup 2)-Isopropylindole-3-acethydrazide
15317-49-4
DTXSID30165237
DTXCID1087728
CHEMBL4584491