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N-Methyltryptamine

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Identification
Molecular formula
C11H14N2
CAS number
61-49-4
IUPAC name
2-(1H-indol-3-yl)-N-methyl-ethanamine
State
State
At room temperature, N-Methyltryptamine is typically in a solid state, specifically appearing as a crystalline powder. It is usually found in a freebase form and is sensitive to air and light.
Melting point (Celsius)
43.00
Melting point (Kelvin)
316.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
174.26g/mol
Molar mass
174.2580g/mol
Density
1.0500g/cm3
Appearence

N-Methyltryptamine typically appears as a white, crystalline solid. However, the compound can sometimes be observed in various other forms such as off-white powders, depending on factors like purity and processing.

Comment on solubility

Solubility of 2-(1H-indol-3-yl)-N-methyl-ethanamine (C11H14N2)

The solubility of 2-(1H-indol-3-yl)-N-methyl-ethanamine is an interesting characteristic largely influenced by its molecular structure and functional groups. As a compound containing both indole and amine functionalities, its solubility properties can be summarized as follows:

  • Polar Nature: Due to the presence of amine groups, this compound exhibits a degree of polarity, which generally enhances solubility in polar solvents.
  • Solvent Compatibility: 2-(1H-indol-3-yl)-N-methyl-ethanamine is likely to be more soluble in organic solvents, such as methanol and ethanol, compared to water, given its hydrophobic indole structure.
  • Concentration Dependency: Its solubility is expected to improve at higher temperatures, a common characteristic for many organic compounds.

In summary, while 2-(1H-indol-3-yl)-N-methyl-ethanamine demonstrates limited solubility in water, its solubility behavior in organic solvents is promising, making it suitable for various applications in biochemical contexts.

Interesting facts

Exploring 2-(1H-indol-3-yl)-N-methyl-ethanamine

2-(1H-indol-3-yl)-N-methyl-ethanamine, often referred to in scientific circles for its intriguing properties, is a fascinating compound that has garnered attention in various fields, particularly in medicinal chemistry and pharmacology.

Key Features

  • Indole Moiety: The indole structure is known for its presence in many natural products and pharmaceuticals. It offers a unique aromatic system that contributes to significant biological activity.
  • Biological Relevance: Compounds like this one play a role in the design of novel therapeutics, particularly those targeting serotonin receptors, which are crucial in the treatment of mood disorders.
  • Methylamino Group: The N-methyl substitution provides an enhancement in the compound’s lipophilicity, potentially improving its ability to cross biological membranes and reach target sites in the body.

Chemical Properties and Applications

This compound has drawn significant interest due to its potential applications, such as:

  • Development of psychoactive substances that mimic natural neurotransmitters.
  • Investigation in the realm of cancer treatments, particularly in relation to indole derivatives known for their anticancer properties.
  • Research into its effects on the central nervous system, which could lead to advancements in understanding various neurological conditions.

Quote from Research

A prominent researcher once stated, “Indole-based compounds are at the forefront of innovative drug design due to their profound biological activities and structural versatility.” This encapsulates the evolving nature of compounds like 2-(1H-indol-3-yl)-N-methyl-ethanamine in contemporary scientific research.

With ongoing studies, this compound is expected to lead to exciting discoveries in therapeutic applications and deepen our understanding of its role in biological systems.

Synonyms
N-Methyltryptamine
61-49-4
3-(2-Methylaminoethyl)indole
2-(1H-Indol-3-yl)-N-methylethanamine
Dipterine
N-Monomethyltryptamine
Methyltryptamine
1H-Indole-3-ethanamine, N-methyl-
N-OMEGA-METHYLTRYPTAMINE
3-(2-(Methylamino)ethyl)indole
N-Methylindoleethylamine
N.omega.-methyltryptamine
UNII-6FRL4L3Z7V
INDOLE, 3-(2-(METHYLAMINO)ETHYL)-
dl-Methyltryptamine
EINECS 200-507-9
6FRL4L3Z7V
BRN 0134134
(2-Indol-3-ylethyl)methylamine
CHEBI:28136
N-methyl-1H-indole-3-ethanamine
1-Methyl-2-(3-indolyl)ethylamine
N(omega)-methyltryptamine
2-(1H-indol-3-yl)-N-methyl-ethanamine
MLS000069493
DTXSID70209846
5-22-10-00047 (Beilstein Handbook Reference)
[2-(1H-indol-3-yl)ethyl](methyl)amine
SMR000059062
Nomega-methyltryptamine
(2-(1H-indol-3-yl)ethyl)(methyl)amine
n-methyl tryptamine
N-methyl-tryptamine
N-w-Methyltryptamine
Maybridge3_003310
cid_6088
Oprea1_433490
BIDD:GT0662
SCHEMBL379409
3-(2-methylaminoethyl)-indole
CHEMBL348588
N-omega-Methyltryptamine, 99%
BDBM30701
DTXCID20132337
HMS1440G10
HMS2235A08
HMS3372P09
3-(N-Methyl-2-amino-ethyl)-indole
CCG-56495
MFCD00005657
AKOS005203036
2-(1H-indol-3-yl)ethyl-methyl-amine
FM64045
IDI1_014697
2-(1H-indol-3-yl)-ethyl-methyl-amine
NCGC00018120-01
NCGC00018120-02
NCGC00018120-03
NCGC00018120-05
1ST166061
DB-053906
NS00014895
C06213
Q308875
SR-01000000029-2
1HU