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Oxindole derivative

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Identification
Molecular formula
C12H13N3O2
CAS number
.null
IUPAC name
2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide
State
State

In its pure form, the compound is solid at room temperature and typically exists in a stable crystalline state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
231.26g/mol
Molar mass
231.2600g/mol
Density
1.2350g/cm3
Appearence

The compound appears as a crystalline white powder. It is often synthesized for use in biochemical research and may exhibit a slightly yellowish hue due to impurities if not purified properly.

Comment on solubility

Solubility of 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide

The solubility of 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide is influenced by several factors that dictate its behavior in various solvents. Understanding its solubility profile can aid in predicting its reactivity and bioavailability. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: The presence of functional groups and their interactions with solvent molecules are crucial. Compounds with polar functional groups tend to be more soluble in polar solvents such as water or methanol.
  • Hydrogen Bonding: The capacity for hydrogen bonding can enhance solubility in polar environments. If 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide can form hydrogen bonds with solvents, solubility will increase.
  • Solvent-Dipole Interactions: Solvent molecules that can interact with dipoles present in the compound may also enhance solubility.
  • Influence of Temperature: As temperature increases, the solubility of many compounds may increase due to enhanced molecular motion, facilitating greater solute-solvent interactions.

In conclusion, it is essential to assess the specific characteristics of 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide to better understand its solubility behavior. Parameters such as solvent choice, temperature, and the potential for interaction play a significant role in determining how well this compound will dissolve in different environments.

Interesting facts

Interesting Facts about 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide

2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide, a compound of notable interest in medicinal chemistry, stands out for its intriguing structural features and potential applications. Here are some engaging insights:

  • Indole Framework: This compound contains the indole moiety, which is widely recognized for its presence in many biologically active compounds and pharmaceuticals. The indole structure offers rich opportunities for diverse chemical reactivity.
  • Hydrazide Functionality: The hydrazide group contributes to the compound's unique reactivity. Hydrazides have been shown to exhibit antimicrobial and anticancer properties, making them formidable candidates in drug design.
  • Biological Activity: Initial research suggests that compounds in this class may possess significant biological activities, including anti-inflammatory and antitumor effects. This makes them of particular interest for further investigation in drug discovery.
  • Potential Derivatives: The presence of dimethyl groups in the structure can enhance lipophilicity, potentially leading to better absorption and bioavailability. This feature opens up avenues for creating novel derivatives with improved therapeutic efficacy.

As noted by many researchers in the field, "The importance of indole derivatives in modern medicinal chemistry cannot be overstated." Such compounds continue to inspire new pathways for treatment strategies in various diseases. Further exploration of 2-(1H-indol-3-yl)-N',N'-dimethyl-2-oxo-acetohydrazide may yield insights that propel it into the spotlight for future therapeutic applications.

In summary, this compound, with its dual functionality and interesting structural characteristics, stands as an inviting subject for both academic exploration and practical drug development!

Synonyms
BRN 0404617
INDOLE-3-GLYOXYLIC ACID, DIMETHYLHYDRAZIDE
unsym-Dimethylhydrazino-3-indolylglyoxamide
5055-38-9
DTXSID70198584
DTXCID30121075