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Chlorhexidine

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Identification
Molecular formula
C22H30Cl2N10Cl2
CAS number
3697-42-5
IUPAC name
2-[[(1R,2R)-2-chlorocyclohexyl]disulfanyl]ethylammonium;chloride
State
State

At room temperature, Chlorhexidine is typically found as either a solid crystalline powder or as part of a liquid solution, especially when prepared for antiseptic use.

Melting point (Celsius)
132.13
Melting point (Kelvin)
405.28
Boiling point (Celsius)
441.10
Boiling point (Kelvin)
714.30
General information
Molecular weight
505.44g/mol
Molar mass
505.4440g/mol
Density
1.0700g/cm3
Appearence

Chlorhexidine appears as a white to yellowish crystalline powder. It is typically odorless and has a bitter taste. It is often available in solution for medical use, appearing as a clear liquid.

Comment on solubility

Solubility of 2-[[(1R,2R)-2-chlorocyclohexyl]disulfanyl]ethylammonium;chloride

The solubility of 2-[[(1R,2R)-2-chlorocyclohexyl]disulfanyl]ethylammonium;chloride is influenced by various factors due to its complex structure. This compound can be categorized under quaternary ammonium salts, and as such, it presents a number of unique solubility characteristics. Here are some key points regarding its solubility:

  • Polar Nature: The presence of the ammonium group contributes to a degree of polarity, often leading to increased solubility in polar solvents such as water.
  • Ionic Interactions: Being a quaternary ammonium salt, it is likely to dissociate in solution, leading to favorable ionic interactions with polar molecules.
  • Organic Solvents: It may also exhibit solubility in organic solvents; however, this is contingent on the solvent's nature and dielectric constant.
  • Hydrophobic Chain: The presence of the cyclohexyl group can affect solubility by introducing hydrophobic characteristics, which may enhance solubility in non-polar solvents.

In summary, while the salt form indicates a tendency for solubility in polar environments, the structural nuances dictate that solubility may vary markedly depending on the solvent used. Thus, experimental determination in various mediums is essential for complete characterization.

Interesting facts

Interesting Facts about 2-[[(1R,2R)-2-chlorocyclohexyl]disulfanyl]ethylammonium;chloride

This intriguing compound belongs to a unique class of organic compounds known for their complex structure and interesting properties:

  • Functional Group Diversity: The presence of disulfanyl (–S–S–) groups combined with an ammonium group suggests potential applications in both organic synthesis and medicinal chemistry. Such functional diversity often leads to interesting reactivity.
  • Stereochemistry: The (1R,2R) configuration indicates a specific spatial arrangement of atoms in the cyclohexyl ring. This stereochemistry can significantly impact the compound's biological activity and interactions, making it a crucial area of study in stereochemistry.
  • Biological Relevance: Compounds similar to this have been studied for their potential therapeutic effects. Researchers are keen on investigating how such structures might interact at the molecular level in biological systems, with implications for drug design and development.
  • Chlorinated Compounds: The chlorine atom in the structure often enhances the compound's stability and lipophilicity, which can affect how the substance interacts with biological membranes and enzymes.
  • Research Applications: With growing interest in materials science, this compound may find its place in the development of novel materials, particularly in the fields of sensors or catalysts due to its unique disulfide linkages.

As one delves into the study of such compounds, the potential is vast, and the intersection of chemistry with biology and materials science becomes increasingly exciting. Scientists are continually exploring how modifications to the molecular structure can lead to enhanced properties and functionalities.

In conclusion, 2-[[(1R,2R)-2-chlorocyclohexyl]disulfanyl]ethylammonium;chloride serves as a reminder of the complexity and beauty inherent in chemical compounds, providing numerous avenues for exploration and innovation.

Synonyms
trans-2-(2-Chlorocyclohexyldithio)ethylamine hydrochloride
trans-2-Aminoethyl 2-chlorocyclohexyl disulfide hydrochloride
ETHYLAMINE, 2-(2-CHLOROCYCLOHEXYLDITHIO)-, HYDROCHLORIDE, E-
27317-89-1
RefChem:345118