Skip to main content

Selegiline

ADVERTISEMENT
Identification
Molecular formula
C13H17N
CAS number
14611-51-9
IUPAC name
2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine
State
State

Selegiline is usually found as a solid at room temperature.

Melting point (Celsius)
141.50
Melting point (Kelvin)
414.65
Boiling point (Celsius)
398.40
Boiling point (Kelvin)
671.55
General information
Molecular weight
187.28g/mol
Molar mass
187.2780g/mol
Density
1.0036g/cm3
Appearence

Selegiline is typically found as a white to off-white powder. It may also appear as crystals, depending on the method of preparation.

Comment on solubility

Solubility of 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine

The solubility of 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine in various solvents can provide key insights into its chemical behavior and potential applications. Understanding its solubility is crucial for several fields, including pharmacology and material science.

Factors Influencing Solubility

Several factors can impact the solubility of this compound:

  • Polarity: The balance of polar and non-polar functional groups affects solubility in polar solvents (e.g., water) versus non-polar solvents (e.g., hexane).
  • Temperature: Increased temperatures often enhance solubility, but the specific effect can vary based on the compound's structure.
  • pH Levels: The solubility may change significantly depending on the acidity or basicity of the solution, due to potential protonation or deprotonation of functional groups.

Expected Solubility Characteristics

In general, compounds containing multiple aromatic rings and amine groups, such as 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine, are anticipated to exhibit:

  • Moderate solubility in organic solvents like ethanol or DMSO.
  • Low solubility in highly polar solvents such as water under standard conditions due to hydrophobic interactions.
  • Potential for interactions with other molecules, especially in biological systems, which could enhance or reduce solubility.

To summarize, the solubility of 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine can vary significantly based on the aforementioned factors, making it a compound of interest for further research in solubility dynamics.

Interesting facts

Interesting Facts about 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine

This compound is a fascinating example of a synthetic organic molecule that can provide insights into both medicinal chemistry and organic synthesis. It is known for its potential applications in pharmacology and various therapeutic contexts. Here are some compelling aspects of this compound:

  • Stereochemistry: The designation (1S,2R) indicates specific spatial configurations of the chiral centers in the molecule. This stereochemical complexity can significantly affect the compound's biological activity and interactions with receptors in the body.
  • Functional Groups: This molecule contains both an ether and an amine functional group. Such combinations often lead to interesting reactivity patterns and can influence the compound's lipophilicity and overall bioavailability.
  • Medicinal Properties: Compounds with similar structural motifs have been studied for their potential as central nervous system agents. The presence of an indane structure may enhance the compound's activity as a neuroprotective agent or in cognitive function enhancement.
  • Research Interest: It has garnered attention in the field of drug discovery, reportedly exhibiting selectivity towards certain neurotransmitter systems, making it a promising candidate for further development.
  • Synthesis Challenges: The synthesis of such compounds often requires multi-step reactions and careful control of reaction conditions to maintain stereochemical integrity. This makes the study of its synthesis an essential topic in advanced organic chemistry courses.

Overall, 2-[(1S,2R)-2-benzylindan-1-yl]oxy-N,N-dimethyl-ethanamine serves as a notable example of how organic chemistry intersects with pharmacology, offering vast potential for future research and application in drug development. Its intricate structure and possible therapeutic uses ignite curiosity and exploration among scientists and chemistry students alike.