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Memantine hydrochloride

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Identification
Molecular formula
C12H22ClNO
CAS number
41100-52-1
IUPAC name
2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride
State
State

At room temperature, memantine hydrochloride is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
215.76g/mol
Molar mass
291.8760g/mol
Density
1.1600g/cm3
Appearence

Memantine hydrochloride appears as a white to off-white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride

The solubility of 2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride is an intriguing topic that merits attention due to its unique chemical structure. This compound, being a hydrochloride salt, exhibits certain characteristics that affect its solubility in various solvents.

Key Points on Solubility:

  • Aqueous Solubility: As a hydrochloride salt, it is generally expected to be soluble in water. This is because hydrochlorides typically enhance the solubility of organic bases.
  • Solvent Dependence: The solubility may vary in different solvents. For example:
    • Polar Solvents: Likely to dissolve well due to the ionic nature of the salt.
    • Non-Polar Solvents: May have limited solubility, as the compound has both polar and non-polar regions in its structure.
  • pH Sensitivity: The solubility could also be influenced by the pH of the solution, as changes in pH may affect the protonation state of the amine group.

In conclusion, while 2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride is expected to be soluble in aqueous environments, the extent and nature of its solubility can be complex and depend on the surrounding conditions. Therefore, conducting specific solubility tests under controlled conditions would provide more definitive insights.

Interesting facts

Exploring 2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride

2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride is a fascinating compound that straddles the fields of organic chemistry and pharmaceutical sciences. This compound is noteworthy for its unique structure and potential applications in medicinal chemistry. Here are some compelling facts about it:

  • Structural Intricacies: The compound features an adamantyl group, which is a hydrocarbon cage structure, providing significant steric hindrance. This property may enhance selectivity in biological interactions.
  • Biological Relevance: Compounds similar to this one have been studied for their effects on the central nervous system, making them of interest in the development of drugs targeting neuropsychiatric disorders.
  • Drug Development: The incorporation of the amine and alcohol functional groups in this molecule signifies its potential as a versatile building block in the synthesis of pharmaceuticals.
  • Research Potential: Ongoing research into similar compounds could yield new insights into their mechanisms of action, specifically how they interact at the molecular level with receptors in the brain.
  • Safety and Regulations: Like many compounds considered for medicinal use, understanding the safety profile and regulatory requirements is crucial for its application in therapeutic settings.

The captivating structure and intriguing potential of 2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride highlight the convergence of chemistry and medicine, paving the way for innovative treatments and therapeutic approaches. As researchers continue to explore its capabilities, the compound’s role in modern science is likely to evolve, making it a point of interest for chemists and pharmacologists alike.

Synonyms
14208-99-2
ADAMANTANE, 1-(2-(2-HYDROXYETHYLAMINO)ETHYL)-, HYDROCHLORIDE
DTXSID10161939
Ethylamine, 2-(1-adamantyl)-N-(2-hydroxyethyl)-, hydrochloride
DTXCID0084430
1-(2-(2-HYDROXYETHYLAMINO)ETHYL)ADAMANTANE HYDROCHLORIDE
2-[2-(1-adamantyl)ethylamino]ethanol;hydrochloride
SCHEMBL6898360