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Oxymetazoline hydrochloride

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Identification
Molecular formula
C16H25ClN2O2
CAS number
2315-02-8
IUPAC name
2-[2-(1-piperidyl)ethoxy]ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate;hydrochloride
State
State

The compound is classified as a solid under room temperature conditions, appearing as a crystalline powder, which is typical for many pharmaceutical agents of its class and formulation.

Melting point (Celsius)
207.90
Melting point (Kelvin)
481.05
Boiling point (Celsius)
507.85
Boiling point (Kelvin)
781.00
General information
Molecular weight
296.80g/mol
Molar mass
296.8010g/mol
Density
1.3668g/cm3
Appearence

The compound appears as an off-white to pale yellow crystalline powder, often reflecting consistency in its manufactured form. Given its hydrophilic properties, it may absorb moisture under high humidity conditions.

Comment on solubility

Solubility of 2-[2-(1-piperidyl)ethoxy]ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate; hydrochloride

The solubility of a compound is a crucial property that can significantly influence its pharmacological activity and applicability. For the compound 2-[2-(1-piperidyl)ethoxy]ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate; hydrochloride, we observe particular characteristics:

  • Hydrochloride Form: The presence of the hydrochloride salt generally enhances the solubility of the compound in aqueous environments due to the formation of ion-dipole interactions.
  • Organic Solvent Compatibility: This compound may demonstrate varying solubility profiles across different organic solvents, which can range from moderate to high depending on the solvent's polarity.
  • Effect of Temperature: Like many organic compounds, increased temperature could lead to improved solubility, an essential factor during formulation processes.
  • Influence of pH: The solubility may also be pH-dependent, with potential variations in solubility observed in acidic or alkaline environments.

In summary, the solubility of this compound is multifaceted and can be influenced by factors such as the ionic nature imparted by the hydrochloride form, temperature, solvent choice, and pH conditions. Understanding these aspects is vital for optimizing its use in various applications.

Interesting facts

Interesting Facts about 2-[2-(1-Piperidyl)ethoxy]ethyl Pyrido[3,2-b][1,4]benzothiazine-10-carboxylate; Hydrochloride

This intriguing compound is a member of the benzothiazine family, which is known for its diverse pharmacological properties. Here are some captivating insights into this particular compound:

  • Pharmacological Potential: Compounds like this one are often explored for their potential therapeutic effects, including actions on CNS (central nervous system) disorders.
  • Structure-Activity Relationship: The complex structure, featuring a pyrido ring fused to a benzothiazine, indicates a potential for the compound to interact with various biological targets in unique ways.
  • Versatility in Synthesis: The synthesis of benzothiazine derivatives has attracted significant interest in medicinal chemistry because of their ability to serve as intermediate scaffolds in drug development.
  • Piperidine Moiety: The piperidine portion not only contributes to the compound's chemical properties but can also enhance lipophilicity, potentially improving the compound's ability to cross biological membranes.
  • Research Applications: This compound may find applications in experimental studies specifically focused on neuropharmacology and the exploration of novel therapeutic agents.

In the realm of medicinal chemistry, the exploration of such compounds can lead to the discovery of new drugs with enhanced efficacy and lower side effects. The subtle interactions facilitated by different functional groups within the structure often trim down the journey of significant medicinal advancements. As with many compounds of its ilk, research into its biological effects may reveal exciting avenues in drug design and development.

In summary, the structural complexity and potential therapeutic implications of 2-[2-(1-Piperidyl)ethoxy]ethyl Pyrido[3,2-b][1,4]benzothiazine-10-carboxylate; hydrochloride make it a fascinating subject of study in the field of chemistry.

Synonyms
Pipazetate hydrochloride
PIPAZETHATE HYDROCHLORIDE
6056-11-7
Theratuss hydrochloride
Pipazethate HCl
757GN3W2CZ
EINECS 227-980-4
NSC 106961
NSC-106961
PIPAZETHATE HYDROCHLORIDE [MI]
PIPAZETATE HYDROCHLORIDE [MART.]
PIPAZETATE HYDROCHLORIDE [WHO-DD]
10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-(1-piperidinyl)ethoxy)ethyl ester, monohydrochloride
10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-piperidinoethoxy)ethyl ester, monohydrochloride
PIPAZETATE HYDROCHLORIDE (MART.)
2-(2-PIPERIDINOETHOXY)ETHYL PYRIDO(3,2-B)(1,4)BENZOTHIAZINE-10-CARBOXYLATE, HYDROCHLORIDE
10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-(1-piperidinyl)ethoxy)ethyl ester, monohydrochloride (9CI)
227-980-4
Selvigon
Pipazethate monohydrochloride
14056-67-8
Pipazethate (hydrochloride)
2-[2-(Piperidin-1-yl)ethoxy]ethyl 10H-pyrido[3,2-b][1,4]benzothiazine-10-carboxylate hydrochloride
2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate;hydrochloride
2-(2-(Piperidin-1-yl)ethoxy)ethyl 10H-pyrido(3,2-b)(1,4)benzothiazine-10-carboxylate hydrochloride
EINECS 237-895-4
UNII-757GN3W2CZ
SCHEMBL8805507
FEUBUXUFKHXRKO-UHFFFAOYSA-N
NSC106961
HY-W742300
CS-0788469
NS00081514
Q27266358
WLN: T C666 BN DN ISJ BVO2O2- AT6NTJ &GH
Ethanol, 10H-pyrido[3,2-B][1,4]benzothiazine-10-carboxylate
Thiophenylpyridylamine-10-carboxylic acid-piperidinoethoxy ethyl ester
10H-Pyrido[3,4]benzothiazine-10-carboxylic acid, 2-(2-piperidinoethoxy)ethyl ester, monohydrochloride
10H-Pyrido[3,4]benzothiazine-10-carboxylic acid, 2-[2-(1-piperidinyl)ethoxy]ethyl ester, monohydrochloride