2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

Identification

Molecular formula

C₁₄H₁₈N₂OS

CAS number

712881-74-4

IUPAC name

2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

State

This compound exists as a solid at room temperature. The state is stable under standard laboratory conditions and should be handled with care to avoid exposure to moisture or other reactive chemicals.

Melting point (Celsius)

173.00

Melting point (Kelvin)

446.15

Boiling point (Celsius)

465.20

Boiling point (Kelvin)

738.35

General information

Molecular weight

262.37g/mol

Molar mass

262.3900g/mol

Density

1.2600g/cm³

Appearence

2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole typically appears as a crystalline solid. The compound can vary in color but is often found as a white to off-white colored solid. It may also exhibit different shades depending on its purity and the presence of impurities.

Comment on solubility

Solubility of 2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

When it comes to the solubility of 2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole, several factors come into play that can influence its behavior in various solvents.

Key Considerations for Solubility:

Polarity: The presence of the piperidyl group may impart some degree of polarity to the compound, affecting its solubility in polar solvents like water.
Solvent Effects: Generally, this compound is expected to be more soluble in organic solvents such as ethanol or dichloromethane compared to polar solvents.
Interactions: The sulfide linkage and aromatic structure could facilitate interactions with other organic molecules, enhancing solubility in specific conditions.

A pertinent observation regarding the solubility characteristics of this compound is its potential classification as a hydrophobic entity, which typically shows limited solubility in water but good solubility in organic solvents. Thus, researchers may consider solubility assays in various media to ascertain its behavior, particularly if it needs to be formulated for biological applications.

In summary, while 2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole may not exhibit high solubility in aqueous environments, its behavior in organic solvents is likely to be much more favorable, making it crucial to test it in multiple solvent systems to fully understand its solubility profile.

Interesting facts

Interesting Facts about 2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is a fascinating compound known for its role in medicinal chemistry. This compound has piqued the interest of researchers due to several notable attributes:

Key Features

Pharmacological Significance: Research indicates that derivatives of benzoxazole are often explored for their potential as therapeutic agents, particularly in the areas of neurodisorders and cancer.
Structural Innovation: The inclusion of a piperidyl group is intriguing, as it adds to the compound's ability to interact with various biological targets, potentially enhancing its efficacy.
Antioxidant Properties: Compounds sharing similar structures have shown antioxidant activity, suggesting this compound may also participate in reducing oxidative stress in biological systems.

Applications and Research

This compound is not only a subject of academic study but also possesses potential applications in pharmaceutical formulations. Some areas of ongoing research include:

Exploring its ability to modulate neurotransmitter activity.
Synthesizing new variants to improve activity and selectivity against specific targets.
Investigating the compound's properties in drug delivery systems.

As researchers delve deeper into the properties of 2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole, the findings may contribute to significant advancements in drug development, showcasing the integral role of chemical compounds in enhancing human health.

Synonyms

2-{[2-(piperidin-1-yl)ethyl]sulfanyl}-1,3-benzoxazole

Oprea1_058570

SCHEMBL13762564

STK112598

AKOS003240642

AG-205/37086002