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Pentoxyverine

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Identification
Molecular formula
C12H16N2O3
CAS number
77-23-6
IUPAC name
2-[2-(1,3-benzodioxol-5-yl)-2-hydroxy-ethyl]guanidine
State
State

At room temperature, pentoxyverine is in a solid state, usually utilized in its crystalline form within pharmaceutical applications.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
499.00
Boiling point (Kelvin)
772.15
General information
Molecular weight
204.23g/mol
Molar mass
204.2280g/mol
Density
1.2081g/cm3
Appearence

Pentoxyverine appears as a white to off-white crystalline powder. It is often odorless, providing easy handling and application in pharmaceutical forms.

Comment on solubility

Solubility of 2-[2-(1,3-benzodioxol-5-yl)-2-hydroxy-ethyl]guanidine

The solubility of 2-[2-(1,3-benzodioxol-5-yl)-2-hydroxy-ethyl]guanidine can be quite intriguing due to the unique structural features it possesses. Generally speaking, the solubility is influenced by various factors, which can be broken down as follows:

  • Polarity: The presence of hydroxyl (-OH) groups increases the polarity, enhancing its affinity for polar solvents such as water.
  • Functional Groups: The guanidine moiety is known for its ability to form hydrogen bonds, which can facilitate solubility in aqueous solutions.
  • Hydrophobic Elements: The benzodioxole ring introduces a hydrophobic segment that may hinder solubility in water but can enhance solubility in organic solvents.

In summary, while the hydroxyl groups suggest a capacity for solubility in polar environments, the overall solubility may be influenced by the balance between hydrophilic and hydrophobic interactions. As one might quote, "the solubility characteristics of a compound often reflect its molecular architecture." Therefore, measuring the solubility across different solvents provides a clearer picture of its behavior in various chemical contexts.

Understanding the solubility of this compound is crucial for its applications in pharmaceuticals and material sciences, where the solvent environment can significantly impact its efficacy and functionality.

Interesting facts

Interesting Facts about 2-[2-(1,3-benzodioxol-5-yl)-2-hydroxy-ethyl]guanidine

This compound, known for its intriguing structure and potential applications, is a member of the guanidine family. Here are some captivating aspects worth noting:

  • Biological Relevance: This molecule is related to various biologically active compounds and demonstrates properties that make it interesting for medicinal chemistry.
  • Natural Compounds: The 1,3-benzodioxole portion of its structure is derived from naturally occurring compounds, and it is often associated with plant-derived substances that exhibit antioxidant properties.
  • Research Potential: Studies suggest that derivatives of this compound might have potential roles in neurological treatments, particularly due to its structural features that enable interactions with biological targets.
  • Synthesis Challenge: The synthesis of this compound often requires advanced techniques and careful reaction conditions. Chemists favor its synthesis as a practical exercise in modern organic synthesis methods.
  • Pharmacological Activity: There is ongoing research regarding its pharmacokinetic profile, making it a candidate for drug development focused on neuroprotection and anti-inflammatory effects.

In summary, 2-[2-(1,3-benzodioxol-5-yl)-2-hydroxy-ethyl]guanidine is not just an ordinary compound. Its unique structure and potential therapeutic implications make it a fascinating subject of study in the field of chemistry and pharmacology.

Synonyms
CHEMBL3301949