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Indalpine

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Identification
Molecular formula
C15H22N2O
CAS number
66869-25-2
IUPAC name
2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol
State
State

At room temperature, Indalpine exists as a solid. It is stable under normal conditions but should be stored away from light and moisture to maintain its integrity.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
257.20
Boiling point (Kelvin)
530.35
General information
Molecular weight
244.36g/mol
Molar mass
244.3380g/mol
Density
1.1480g/cm3
Appearence

Indalpine typically presents as a white crystalline powder. It is synthesized for pharmaceutical applications and may vary slightly in appearance depending on its form and purity.

Comment on solubility

Solubility of 2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol

The solubility of 2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol in various solvents provides significant insights into its chemical behavior. This compound exhibits a moderate solubility profile due to its unique structural features. Here are key points regarding its solubility:

  • Polar Solvents: The presence of an alcohol functional group makes it soluble in polar solvents such as water and methanol, which can interact favorably with the hydroxyl group.
  • Non-Polar Solvents: Solubility in non-polar solvents may be limited, as the compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions.
  • Temperature Influence: Solubility may increase with temperature, often enhancing the dissolution of the compound in solvents.
  • pH Dependence: The solubility can vary significantly with changes in pH, particularly due to the amine group, which can become protonated in acidic solutions, increasing solubility.

In summary, understanding the solubility of this compound is crucial for its application in various chemical and biological contexts. As with many compounds, the solubility profile is highly dependent on the nature of the solvent and external conditions, making it a fascinating area of study.

Interesting facts

Exploring the Intricacies of 2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol

The compound 2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol, often a point of interest in medicinal chemistry, illustrates the fascinating intersection of organic chemistry and pharmacology. Structurally, it incorporates an indole ring, a common motif in many biologically active compounds, that contributes to its potential pharmacodynamic properties. Here are some intriguing aspects of this compound:

  • Indole Influence: The presence of the indole moiety is not just for show; it significantly affects the compound's interactions with biological systems. Indole-based compounds have been widely studied for their roles in neurotransmitter modulation.
  • Ethyl and Isopropyl Groups: The substituted ethyl and isopropyl groups enhance the lipophilicity of the compound, potentially influencing its ability to cross biological membranes and reach target sites within organisms.
  • Amine Functionality: The amine in the structure may provide sites for hydrogen bonding with biological targets, which is vital for the binding and efficacy of drug candidates.
  • Pharmacological Potential: Due to its unique structural elements, this compound holds promise for therapeutic activity, particularly in the treatment of neurological disorders, though further research is needed to clarify its mechanisms.

In summary, 2-[2-(1H-indol-3-yl)ethyl-isopropyl-amino]ethanol stands as a testament to the complex relationship between chemical structure and biological function. Its study paves the way for potential advancements in drug development, making it a compound worth investigating further. As noted by researchers, "The closer we look, the more intricacies we discover in the realms of organic compounds and their biological capabilities."

Synonyms
7384-94-3
BRN 0399315
ETHANOL, 2-(N-(2-(3-INDOLYL)ETHYL)-N-ISOPROPYLAMINO)-
2-(N-(2-Hydroxyethyl)-N-isopropylamino)ethylindole
2-(N-(2-(3-Indolyl)ethyl)-N-isopropylamino)ethanol
Indole, 2-(N-(2-hydroxyethyl)-N-isopropylamino)ethyl-
DTXSID40224389
5-22-10-00056 (Beilstein Handbook Reference)
DTXCID90146880
2-((2-(1H-indol-3-yl)ethyl)(isopropyl)amino)ethan-1-ol