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Almotriptan

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Identification
Molecular formula
C17H25NOS
CAS number
154323-57-6
IUPAC name
2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine
State
State

At room temperature, Almotriptan is generally found in a solid state as a crystalline powder.

Melting point (Celsius)
136.40
Melting point (Kelvin)
409.55
Boiling point (Celsius)
313.30
Boiling point (Kelvin)
586.45
General information
Molecular weight
335.46g/mol
Molar mass
335.5040g/mol
Density
0.9230g/cm3
Appearence

Almotriptan typically appears as a white to off-white powder.

Comment on solubility

Solubility of 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine

The solubility of complex organic compounds such as 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine can be quite variable, influenced by numerous factors. These may include:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents.
  • Hydrogen Bonding: Capable of forming hydrogen bonds, this compound might exhibit increased solubility in protic solvents like water.
  • Molecular Size: Larger molecules can fare differently than smaller ones; hence the bulky naphthyl group may hinder its solubility.
  • Solvent Choice: Its solubility can be assessed in various organic solvents such as ethanol, methanol, or dichloromethane.

Interestingly, solubility is often reported in terms of “like dissolves like”, which emphasizes that a solvent’s chemical nature plays a vital role in dissolving a substance. Furthermore, temperature may also significantly impact solubility; generally, an increase in temperature can lead to increased solubility for many solid compounds.

In conclusion, while detailed solubility data may be sparse, systematic studies and considerations can provide insights into how 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine interacts with different solvents.

Interesting facts

Interesting Facts about 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine

The compound 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine is a fascinating example of complex molecular architecture. It belongs to a category of compounds that reflect the intersection of organic synthesis, medicinal chemistry, and pharmacology. Here are several intriguing aspects:

  • Synthetic Complexity: This compound illustrates a sophisticated synthetic approach, featuring multiple functional groups including a piperidine ring and a naphthyl moiety.
  • Potential Biological Activity: The presence of a tetrahydrofuran ring and a sulfur atom suggests that this compound could be a candidate for biological assays, potentially exhibiting properties valuable in neuropharmacology or as analgesics.
  • Structural Diversity: The naphthylmethyl group adds significant structural diversity, which is crucial in drug design. Such functional groups often enhance binding interactions with biological targets.
  • Multidisciplinary Appeal: This compound invites interest from various fields, including medicinal chemistry, where understanding the interactions between such complex molecules and biological systems can lead to novel therapeutic agents.

In conclusion, compounds like 2-[2-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]sulfanylethyl]piperidine serve as compelling examples of the intricate relationships between chemistry and biology, underscoring the importance of structural features in determining a compound's behavior and potential applications in medicine.