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Trospium Chloride

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Identification
Molecular formula
C25H30ClNO3
CAS number
10405-02-4
IUPAC name
2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium
State
State

At room temperature, trospium chloride is in a solid state. It is often found in powder form and is used in various pharmaceutical formulations such as tablets or capsules.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
427.97g/mol
Molar mass
427.9720g/mol
Density
1.2350g/cm3
Appearence

Trospium chloride is typically a white or almost white crystalline powder. It is highly soluble in water and appears clear and transparent when dissolved.

Comment on solubility

Solubility of 2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium

The solubility of 2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium can be quite complex due to its unique structural features. With compounds like this, several factors play a crucial role in determining their solubility:

  • Polarity: The presence of functional groups such as hydroxyl (-OH) and ammonium (-N+) significantly affects solubility in polar solvents like water.
  • Hydrophobic regions: The bicyclic structure and phenyl groups contribute to hydrophobic characteristics, making the compound less soluble in polar solvents.
  • Concentration: At higher concentrations, solubility may decrease due to intermolecular attractions or aggregation.

Generally, compounds with cationic ammonium groups can exhibit water solubility, but the overall structure suggests that 2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium may have limited solubility in water while being more soluble in organic solvents. An insightful quote to bear in mind is, “Like dissolves like,” indicating that similar polarities can enhance solubility.

In studies and applications, understanding the solubility of such compounds is critical for their effective use, especially in pharmaceuticals and materials science. Thus, experimentation under various conditions (temperature, pH, solvent) is essential to determine the precise solubility characteristics of this compound.

Interesting facts

Interesting Facts about 2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium

This fascinating compound is a member of the quaternary ammonium class, known for its significant role in various chemical processes. Its complex structure showcases the interrelationship between organic and inorganic chemistry, involving intricate cyclic systems and functional groups. Here are some notable aspects of this compound:

  • Quaternary Ammonium Compounds: These are known for their antibacterial properties and are commonly used in antiseptic and disinfecting agents. The positively charged nitrogen makes them highly effective in disrupting microbial membranes.
  • Structural Diversity: The compound features a bicyclic structure that contributes to its unique chemical behavior. The bicyclo[2.2.1]heptene configuration allows for intriguing reactivity and can facilitate various synthetic pathways.
  • Pharmaceutical Applications: Compounds with similar structures have been explored for their potential in drug delivery systems and as surfactants, thanks to their amphiphilic nature.
  • Hydroxyl and Acetyl Groups: The presence of hydroxy and acetyl functionalities suggests interactions through hydrogen bonding, which can enhance solubility and stability in different solvents.

As a *chemistry student*, studying this compound unlocks insights into:

  1. **Reactiveness of quaternary ammonium salts in organic transformations**
  2. **The significance of structural configuration in determining compound behavior**
  3. **Potential synthesis pathways involving bicyclic compounds and their derivatives**

In conclusion, 2-[2-(2-bicyclo[2.2.1]hept-2-enyl)-2-hydroxy-2-phenyl-acetyl]oxyethyl-trimethyl-ammonium is not just a name; it embodies the intricate dance of atoms that leads to functional materials used across various fields, including medicine and industrial chemistry.