Chlormethine hydrochloride | Solubility of Things

Identification

Molecular formula

C₅H₁₁Cl₂N₃O₂

CAS number

55-86-7

IUPAC name

[2-[2-[[2-[bis(2-chloroethyl)ammonio]acetyl]amino]ethylamino]-2-oxo-ethyl]-bis(2-chloroethyl)ammonium;dichloride

State

At room temperature, chlormethine hydrochloride is a solid. It is typically stored under cool and dry conditions to maintain its stability and efficacy.

Melting point (Celsius)

37.00

Melting point (Kelvin)

310.15

Boiling point (Celsius)

330.00

Boiling point (Kelvin)

603.15

General information

Molecular weight

304.55g/mol

Molar mass

304.5450g/mol

Density

1.4475g/cm³

Appearence

Chlormethine hydrochloride appears as a white crystalline powder. It is a hygroscopic compound, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-[2-[[2-[bis(2-chloroethyl)ammonio]acetyl]amino]ethylamino]-2-oxo-ethyl]-bis(2-chloroethyl)ammonium;dichloride

The solubility of the compound 2-[2-[[2-[bis(2-chloroethyl)ammonio]acetyl]amino]ethylamino]-2-oxo-ethyl]-bis(2-chloroethyl)ammonium;dichloride is a significant characteristic that can influence its applications and behavior in various environments. Here are some essential points regarding its solubility:

Solvent Dependency: The solubility may vary substantially in different solvents. Generally, ionic compounds tend to be soluble in polar solvents, particularly water.
Charged Nature: As this compound contains multiple charged entities, it is likely to display good solubility in aqueous solutions.
Temperature Influence: Increased temperature often enhances solubility for many compounds, enabling a more substantial dissolution in warmer conditions.
pH Effects: The acidic or basic nature of the medium can also impact solubility; for instance, increasing acidity may facilitate the ionization of the ammonium groups, potentially enhancing solubility.

In summary, while the specific solubility of this compound requires further empirical study in various solvents, one can anticipate that its ionic characteristics will lead to notable solubility in polar environments, particularly those that are aqueous. Understanding these solubility traits can be crucial for its practical applications in chemical processes and formulations.

Interesting facts

Interesting Facts About the Compound

This fascinating compound, known as 2-[2-[[2-[bis(2-chloroethyl)ammonio]acetyl]amino]ethylamino]-2-oxo-ethyl]-bis(2-chloroethyl)ammonium; dichloride, holds significant importance in various fields of chemistry and medicine. Here are some engaging insights:

Chemotherapy Applications: The potent structure of this compound allows it to act as a chemotherapy agent. Its ability to target cancer cells has made it a subject of extensive research in oncology.
Mechanism of Action: The compound is noted for its alkylating properties, disrupting DNA synthesis, which prevents the proliferation of rapidly dividing cancer cells.
Enhanced Efficacy: The incorporation of bis(2-chloroethyl) groups enhances the molecule's reactivity towards nucleophilic sites in DNA, amplifying its therapeutic potential.
Drug Resistance: Researchers are actively investigating how this compound can combat drug resistance mechanisms commonly seen in cancer treatments.
Multi-functional Design: The intricate design of this compound illustrates the beauty of synthetic chemistry, where functional groups are skillfully integrated to enhance pharmacological activity.

As a compound that continues to inspire scientific inquiry, it embodies the intersection of chemistry and medicine, showcasing how chemical knowledge can lead to transformative therapies. Delving into the study of such compounds not only broadens our understanding of chemical interactions but also signifies hope in the relentless fight against cancer.

Synonyms

N,N'-Ethylenebis((bis(2-chloroethyl)amino)acetamide) dihydrochloride

ACETAMIDE, N,N'-ETHYLENEBIS((BIS(2-CHLOROETHYL)AMINO)-, DIHYDROCHLORIDE

N,N'-Ethylene-2,2'-bis(bis(2-chloroethyl)amino)bisacetamide dihydrochloride

1697-05-8