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Brotizolam

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Identification
Molecular formula
C15H19BrN3O5
CAS number
57801-95-3
IUPAC name
[2-[2-(2-bromo-6-methoxy-benzoyl)pyrrol-1-yl]-1-methyl-ethyl]-dimethyl-ammonium;2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate
State
State

At room temperature, brotizolam is a solid. It is stable under normal conditions and typically stored in a dry, well-ventilated area away from light and moisture.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
272.00
Boiling point (Kelvin)
545.15
General information
Molecular weight
388.24g/mol
Molar mass
388.2430g/mol
Density
1.0300g/cm3
Appearence

Brotizolam typically appears as a white to slightly yellow crystalline powder. It is known for its translucency and might exhibit a slight sheen under light due to its crystalline structure.

Comment on solubility

Solubility of the Compound

The solubility of the compound [2-[2-(2-bromo-6-methoxy-benzoyl)pyrrol-1-yl]-1-methyl-ethyl]-dimethyl-ammonium;2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate can be influenced by various factors. Understanding its solubility properties is crucial for its application in various fields, such as pharmaceuticals and chemical research.

Key Factors Affecting Solubility

  • Polarity: The presence of charged functional groups, such as the ammonium and carboxymethyl moieties, often increases solubility in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl groups in the structure may engage in hydrogen bonding with solvent molecules, enhancing solubility.
  • Size of the Molecule: Larger and more complex molecules may exhibit lower solubility in some solvents compared to smaller, simpler compounds.

Additionally, it is noteworthy that:

  • Polar solvents are generally more effective at dissolving ionic or charged compounds.
  • Solubility may vary with temperature, as increased temperatures can promote solubility for certain compounds.

In conclusion, the intricate balance of these factors will determine the solubility of this compound in different solvents, making it an essential consideration for chemists and researchers aiming to utilize it effectively in their formulations and applications. As always, empirical testing is highly recommended to confirm solubility in specific conditions.

Interesting facts

Interesting Facts about 2-[2-(2-bromo-6-methoxy-benzoyl)pyrrol-1-yl]-1-methyl-ethyl]-dimethyl-ammonium; 2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate

This compound is a fascinating example of a complex organic molecule that merges aspects of medicinal chemistry and material science. It features various functional groups that lend it unique properties and potential applications. Here are some intriguing aspects to consider:

  • Multifunctionality: The presence of both a pyrrole moiety and a bromo-substituted aromatic ring opens up avenues for reactivity and interaction with biological macromolecules, making it an enticing candidate for pharmaceuticals.
  • Antimicrobial Potential: Compounds containing bromo and methoxy groups have been evaluated for their antimicrobial activities. Research into similar structures suggests that they may exhibit significant effects against various pathogens.
  • Chirality and Synthesis: The optically active nature of ammonium derivatives contributes to their chiral characteristics, which can be crucial in drug design. As chemists, creating enantiopure compounds is a fundamental goal in realizing enhanced therapeutic efficacy.
  • Biocompatibility: The inclusion of carboxymethyl and hydroxyl groups in the compound enhances its potential biocompatibility, making it suitable for pharmaceutical applications where safety is paramount.
  • Research Opportunities: Molecules like this offer exciting prospects for research into drug delivery systems and targeted therapy, where the specific interactions with biological targets can lead to better outcomes in treatment methodologies.

As we explore such complex compounds, it's essential to contemplate not only their synthesis and characterization but also the broader implications they hold in fields like drug discovery and bioengineering. Chemists and researchers advocate for a deeper understanding of these interactions to unlock the full potential of such exciting compounds.

Synonyms
2-(5-Bromo-2-methoxybenzoyl)-1-(2-(dimethylamino)propyl)pyrrole citrate
7054-85-5
KETONE, 5-BROMO-2-METHOXYPHENYL 1-(2-(DIMETHYLAMINO)PROPYL)PYRROL-2-YL, CITRATE