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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23N2O2Cl
CAS number
6108-05-0
IUPAC name
2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium
State
State

At room temperature, lidocaine hydrochloride is typically found in a solid state in the form of a crystalline powder.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
270.80g/mol
Molar mass
270.7990g/mol
Density
1.0060g/cm3
Appearence

Lidocaine hydrochloride is a white to off-white crystalline powder. It is highly soluble in water and in alcohol. Its solutions are typically clear and colorless.

Comment on solubility

Solubility of 2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium

The solubility of this compound is influenced by its complex structure, which incorporates multiple functional groups that can interact with solvents in various ways. Key considerations for its solubility include:

  • Polarity: The presence of ammonium groups suggests a potential for ionic interactions, which may enhance solubility in polar solvents, such as water.
  • Hydrophobic regions: The (2-methoxyphenyl)methyl groups introduce hydrophobic characteristics, which may limit solubility in non-polar solvents.
  • Hydrogen bonding: Functional groups capable of forming hydrogen bonds could facilitate interactions with solvent molecules, increasing solubility.
  • Temperature: Solubility can be temperature-dependent; higher temperatures may increase solubility due to enhanced molecular movement.

In summary, while the ammonium groups may promote solubility in polar environments, the overall solubility behavior of this compound will likely be a balance between its polar and non-polar characteristics. Experimentation is essential to accurately characterize its solubility profile.

Interesting facts

Interesting Facts about 2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium

This compound is a fascinating example of a synthetic organic molecule that showcases the complexity and elegance found in organic chemistry. Often referred to in the context of its potential applications in medicinal chemistry, it embodies intricate structural features that allow for a variety of interactions at a molecular level.

Structural Highlights

  • Quaternary Ammonium Ion: The presence of a quaternary ammonium ion often contributes to the compound's biological activity, allowing for interactions with various biological membranes.
  • Aromatic Methoxy Substituents: The 2-methoxyphenyl groups can enhance lipophilicity, potentially increasing the compound's efficacy in pharmaceuticals.
  • Unique Functional Groups: The combination of diethyl amino groups and acetyl linkages grants unique reactivity profiles that may be exploited in drug design.

Potential Applications

This compound may serve various applications, including:

  1. Pharmaceutical Development: Its complex structure could be tailored to target specific diseases, potentially leading to the development of new therapeutic agents.
  2. Research Tools: Compounds like this are often used in drug research to understand their biological mechanisms and effects.

Scientific Insights

Understanding compounds of this nature requires a deep dive into methods of synthesis, reactivity, and mechanistic studies. As noted by chemists, “The key to unlocking the potential of synthetic compounds lies in their ability to be fine-tuned at the molecular level.” Through structural modifications, scientists can increase potency, selectivity, and reduce side effects of the resulting drugs.

In conclusion, the compound 2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]ammonio]ethylamino]-2-oxo-acetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]ammonium is more than just a collection of atoms; it represents the cutting edge of chemical research and its potential for impactful real-world applications.

Synonyms
Methoxyambenonium
13015-59-3
DTXSID90156368
Ammonium, (oxalylbis(iminoethylene))bis(diethyl(o-methoxybenzyl)-
2-[[2-[2-[diethyl-[(2-methoxyphenyl)methyl]azaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl-diethyl-[(2-methoxyphenyl)methyl]azanium
Benzenemethanaminium, N,N'-((1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl))bis(N,N-diethyl-2-methoxy-
DTXCID2078859