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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
[2-[2-[(2-hydroxy-3-methoxy-phenyl)methylene]hydrazino]-2-oxo-ethyl]-trimethyl-ammonium
State
State

At room temperature, curcumin is typically found in a solid state. It manifests as a crystalline powder owing to its complex molecular structure.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
610.00
Boiling point (Kelvin)
883.15
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.4500g/cm3
Appearence

Curcumin is a bright yellow crystal or crystalline powder that is often recognized for its vibrant color. It is commonly used as a dye, which is evident in its strong and intense yellow hue.

Comment on solubility

Solubility Insights for the Compound

The solubility of the compound 2-[2-[(2-hydroxy-3-methoxy-phenyl)methylene]hydrazino]-2-oxo-ethyl]-trimethyl-ammonium can be influenced by several factors inherent to its structure:

  • Polarity: As a quaternary ammonium compound, it features ionic characteristics, which often enhance solubility in polar solvents such as water.
  • Functional Groups: The presence of multiple functional groups, including the hydroxy and methoxy moieties, can contribute to hydrogen bonding, further impacting solubility.
  • Hydration: Ionic compounds typically interact favorably with water molecules, leading to potential high solubility.

In summary, it is likely that this compound exhibits good solubility in polar solvents due to the combination of ionic and hydrogen bonding characteristics. However, precise solubility data would be beneficial for a complete understanding. To evoke a deeper comprehension, it's noteworthy that “like dissolves like” remains a guiding principle—a concept particularly relevant here.

Interesting facts

Interesting Facts About 2-[2-[(2-hydroxy-3-methoxy-phenyl)methylene]hydrazino]-2-oxo-ethyl]-trimethyl-ammonium

This compound is a fascinating example of a quaternary ammonium compound, a class that has significant industrial and biological relevance. Its intricate structure showcases a blend of functional groups, making it a compound of interest in various fields of research.

1. Biological Importance

  • Antimicrobial Activity: Quaternary ammonium compounds are well-known for their antimicrobial properties, which can make this compound useful in developing antiseptics and disinfectants.
  • Pharmaceutical Applications: The unique functional groups in the structure suggest potential applications in drug design and delivery systems, especially for targeting certain types of cells or tissues.

2. Synthetic Approaches

The complexity of this compound indicates that it likely requires sophisticated synthetic methods for its preparation. Researchers often explore various pathways to optimize yields and purity.

3. Structure-Activity Relationship

  • Hydrazone Linkage: The presence of a hydrazone bond adds intriguing features, as these linkages can influence the compound's reactivity and stability.
  • Hydroxyl Group: The inclusion of the hydroxyl group can enhance solubility in biological systems, while the methoxy group may influence lipid bilayer permeability.

4. Research Applications

This compound serves as a model for studying hydrogen bonding and intermolecular interactions, which are critical for understanding various chemical and biological processes.

In summary, 2-[2-[(2-hydroxy-3-methoxy-phenyl)methylene]hydrazino]-2-oxo-ethyl]-trimethyl-ammonium is not just a chemical formula but a doorway to exploring advanced materials and medicinal chemistry. As scientists continue to investigate its properties, the potential uses in health and technology remain a topic of significant interest.

Synonyms
NCIOpen2_008021