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Pyrroloquinoline quinone (PQQ)

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Identification
Molecular formula
C14H6N2O8
CAS number
72909-34-3
IUPAC name
2-[2-(2-methoxybenzoyl)pyrrol-1-yl]ethyl-dimethyl-ammonium;chloride
State
State
At room temperature, Pyrroloquinoline quinone typically exists as a solid powder. This is convenient for its use in dietary supplements and various experimental applications.
Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
540.80
Boiling point (Kelvin)
814.00
General information
Molecular weight
330.31g/mol
Molar mass
330.3100g/mol
Density
1.1537g/cm3
Appearence
Pyrroloquinoline quinone (PQQ) typically appears as a pale yellow powder. It is often used in its salt form, which can influence the specific color and consistency observed.
Comment on solubility

Solubility of 2-[2-(2-methoxybenzoyl)pyrrol-1-yl]ethyl-dimethyl-ammonium; chloride

The solubility of 2-[2-(2-methoxybenzoyl)pyrrol-1-yl]ethyl-dimethyl-ammonium; chloride can be influenced by several factors, including its chemical structure and the nature of the solvent used. Generally, the ammonium component suggests that the compound is likely to be soluble in polar solvents such as water. Some important points to consider are:

  • Polarity: The presence of quaternary ammonium groups typically enhances solubility in polar solvents.
  • Hydrophilicity: The substitution with the methoxy group may impact the overall hydrophilic/hydrophobic balance, potentially making the compound less soluble in non-polar solvents.
  • pH Dependency: The solubility may also vary with pH levels; it could be significantly more soluble under certain acidic or basic conditions.
  • Concentration Effects: In concentrated solutions, solubility limits could be affected, leading to precipitation under certain conditions.

In summary, while this compound is expected to be soluble in polar solvents, its unique structure can lead to variability in solubility based on environmental factors. Testing in different solvents and conditions is advisable to accurately determine the solubility profile.

Interesting facts

Interesting Facts about 2-[2-(2-methoxybenzoyl)pyrrol-1-yl]ethyl-dimethyl-ammonium;chloride

This intriguing compound is notable for its structural complexity and unique properties, making it a subject of interest in various scientific fields. Here are some key highlights:

  • Pharmaceutical Potential: Compounds with piperidine and pyrrole motifs have been extensively studied for their potential biological activities, including antimicrobial and anticancer effects. This compound's structure suggests a possible role in medicinal chemistry.
  • Organosilicon Chemistry: The presence of the methoxy group may enhance solubility and bioavailability, which is crucial in drug development, demonstrating the intricate relationship between chemical structure and function.
  • Ionic Interactions: As a quaternary ammonium salt, this compound can participate in strong ionic interactions. These interactions are significant in various applications, from surfactants to drug delivery systems.
  • Research Applications: The unique combination of functional groups in this compound opens up avenues for exploring its use in various experiments in both organic synthesis and materials science.
  • Language of Chemistry: This compound exemplifies the vast vocabulary of chemistry, showcasing how names can convey complex structures and functionalities. Each part of the name informs scientists about specific parts of its chemical behavior.

"The beauty of chemistry lies in the ability to design molecules that can serve specific purposes in science and medicine." This compound is a great illustration of such design, emphasizing the creativity and innovation innate to the field.

As researchers continue to explore the potential applications of this compound, it holds promise for significant contributions to chemistry, biology, and pharmacology.

Synonyms
1-(2-(Dimethylamino)ethyl)-2-(o-methoxybenzoyl)pyrrole monohydrochloride
14415-61-3
KETONE, 1-(2-(DIMETHYLAMINO)ETHYL)PYRROL-2-YL o-METHOXYPHENYL, HYDROCHLORIDE