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Oxymetazoline

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Identification
Molecular formula
C16H24N2O
CAS number
2315-02-8
IUPAC name
2-[2-(2-methyl-1-piperidyl)ethyl]guanidine
State
State

Oxymetazoline is in a liquid state at room temperature. It is commonly formulated in aqueous solutions for use as a nasal decongestant.

Melting point (Celsius)
-3.50
Melting point (Kelvin)
269.65
Boiling point (Celsius)
241.00
Boiling point (Kelvin)
514.15
General information
Molecular weight
260.38g/mol
Molar mass
261.3690g/mol
Density
1.0800g/cm3
Appearence

Oxymetazoline appears as a clear to slightly yellowish liquid. Its consistency is generally viscous, and it is typically found in decongestant nasal sprays in small concentrations.

Comment on solubility

Solubility of 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine

The solubility of 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine is an interesting aspect to consider, as it can influence its application in various fields such as pharmaceuticals and chemical synthesis. This compound is generally characterized by the following solubility characteristics:

  • Water Solubility: It is expected that 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine exhibits moderate to high solubility in water due to the presence of the guanidine functional group, which can form strong interactions with water molecules.
  • Solubility in Organic Solvents: The compound may also demonstrate solubility in various organic solvents, particularly polar solvents such as ethanol and methanol, owing to its hydrophilic and lipophilic balance.
  • Influence of pH: The solubility can further be influenced by the pH of the solution, as guanidine derivatives typically carry protonatable amine groups.

As a general rule, it is crucial to conduct empirical tests to determine the exact solubility under desired conditions since factors like temperature and pressure can also affect solubility. In conclusion, the solubility profile of 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine is multifaceted, making it a valuable candidate for further exploration in solubility-related studies.

Interesting facts

Interesting Facts About 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine

2-[2-(2-methyl-1-piperidyl)ethyl]guanidine is a fascinating compound that has garnered attention in the fields of pharmacology and medicinal chemistry due to its unique structure and potential therapeutic applications. Here are some intriguing points about this compound:

  • Structure and Functionality: The presence of a guanidine group, along with a piperidine moiety, allows for multiple avenues of interaction with biological systems, making it a valuable model for studying receptor activity.
  • Biological Activity: This compound has been investigated for its effects on neurotransmitter systems, with research indicating potential roles in modulating acetylcholine and serotonin receptors, which are critical for numerous neural processes.
  • Drug Development: The structural characteristics of 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine make it a candidate for further exploration in the development of new drugs targeting neurological disorders.
  • Historical Significance: Guanidine derivatives have a rich history in organic and medicinal chemistry, with many compounds derived from guanidine being used for their diverse pharmacological properties.
  • Research Potential: Ongoing studies aim to elucidate the precise mechanism by which this compound acts in the central nervous system, potentially leading to breakthroughs in treatments for conditions like depression and anxiety.

In summary, 2-[2-(2-methyl-1-piperidyl)ethyl]guanidine exemplifies the intricate relationship between structure and function in medicinal chemistry. Its unique configuration not only highlights the innovative capabilities of chemists but also underscores the continuous journey of discovery within the pharmaceutical sciences.