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AMG-9810

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Identification
Molecular formula
C14H30N4
CAS number
477600-74-1
IUPAC name
2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine
State
State

At room temperature, this compound is in solid state. It is typically stable under standard ambient conditions.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.20
Boiling point (Celsius)
428.70
Boiling point (Kelvin)
701.90
General information
Molecular weight
252.43g/mol
Molar mass
252.4280g/mol
Density
0.8703g/cm3
Appearence

AMG-9810 typically appears as a white to off-white powder. The compound is generally supplied in solid form and is known for its stability under normal conditions.

Comment on solubility

Solubility of 2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine

The solubility of 2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine in various solvents can be quite intriguing due to its unique chemical structure. This compound is known to exhibit different solubility characteristics depending on the solvent used:

  • Water: The solubility in water is generally low, which may limit its utility in aqueous environments.
  • Organic Solvents: It has a higher affinity for organic solvents such as ethanol and methanol. This may make it suitable for applications requiring organic solvent environments.
  • pH Dependence: The solubility may also be affected by the pH of the solution due to the presence of the guanidine functional group, which can protonate under acidic conditions.

Overall, the solubility behavior of 2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine illustrates the importance of chemical structure on solubility properties. As noted in solubility studies, "the more complex the molecular architecture, the more variable the solubility tends to be." This compound is an excellent example of such complexity, leading to a diverse range of solubility profiles.

Interesting facts

Interesting Facts about 2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine

This fascinating compound, known for its unique structure and properties, falls under the category of guanidine derivatives, which are of significant interest in both medicinal chemistry and materials science. Here are some noteworthy aspects:

  • Structural Diversity: The presence of the tetramethyl-1-piperidyl group adds structural complexity and hydrophobic character to the molecule, enhancing its interaction potential with biological targets.
  • Biological Activity: Guanidine derivatives are widely studied for their pharmacological properties. This compound may exhibit potential as a therapeutic agent, particularly in neurological applications, due to its interaction with various receptors.
  • Chemical Reactivity: The guanidine functional group is known for its basicity and reactivity, making it a versatile building block in organic synthesis.
  • Applications in Research: It serves as a significant precursor in designing other bioactive compounds or materials, paving the way for innovative applications in drug discovery and development.
  • Impact on Physical Properties: The steric hindrance introduced by the tetramethyl group influences the solubility and stability of the compound, which is crucial for its potential application in pharmaceutical formulations.

The intriguing structure of 2-[2-(2,2,6,6-tetramethyl-1-piperidyl)ethyl]guanidine not only showcases the beauty of chemical synthesis but also emphasizes the importance of guanidine compounds in advancing our understanding of biological systems and developing new therapeutic agents.