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Zibotentan

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Identification
Molecular formula
C13H19N3O2
CAS number
186497-07-4
IUPAC name
2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine
State
State

At room temperature, zibotentan is in a solid state.

Melting point (Celsius)
213.80
Melting point (Kelvin)
486.90
Boiling point (Celsius)
437.20
Boiling point (Kelvin)
710.20
General information
Molecular weight
295.35g/mol
Molar mass
295.3520g/mol
Density
1.3250g/cm3
Appearence

Zibotentan is typically found as a solid powder. It appears as an off-white to pale yellow crystalline substance.

Comment on solubility

Solubility of 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine

The solubility of 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine can be an intriguing topic due to its unique structure. This compound belongs to the class of guanidines, known for their diverse applications in pharmaceutical chemistry. However, understanding its solubility is crucial for optimal use in formulations.

  • Polarity: The presence of both hydrophobic (benzodioxin) and hydrophilic (guanidine) portions in the molecular structure significantly affects solubility. This dual character may lead to variable solubility in different solvents.
  • Solvent Compatibility: Generally, compounds featuring aromatic systems, like benzodioxin, may exhibit better solubility in organic solvents (e.g., ethanol, methanol) compared to water.
  • Temperature Influence: Solubility can also be influenced by temperature; increased temperatures often enhance solubility for many organic compounds.

In summary, while 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine's solubility profile is highly dependent on external conditions, understanding these nuances can guide its application in various fields. As the compound interacts with different solvent environments, its solubility will continue to be an area ripe for investigation.

Interesting facts

Exploring 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine

2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine is a fascinating compound that captures the attention of many chemists due to its unique structure and potential applications. Here are some interesting facts that highlight its significance:

  • Novel Structure: This compound features a complex arrangement, incorporating both guanidine and a benzodioxin moiety. The presence of the benzodioxin—known for its aromatic properties—adds an intriguing layer to its chemical behavior.
  • Biological Activity: Compounds containing guanidine functional groups are often studied for their biological activity, including antimicrobial and antiviral properties. The distinctive structure of 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine makes it a candidate for further investigation in drug design.
  • Applications in Materials Science: The versatile nature of this compound suggests potential uses in polymers and materials with specific functions, such as conductivity or adhesive properties.
  • Synthesis Challenges: The synthesis of 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine raises interesting challenges for chemists. The complexity of the benzodioxin structure requires skillful manipulation of synthetic techniques, often involving multi-step processes and protecting group strategies.
  • Research Opportunities: With the ongoing exploration of guanidine derivatives in pharmaceuticals, this compound presents ample opportunities for research. Its interaction with biological targets could pave the way for innovative therapies and experimental studies.

As we delve deeper into the chemistry of 2-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]guanidine, we uncover not only profound insights into its properties but also the potential to inspire future innovations in both medicinal chemistry and materials science. The interplay between its unique structure and possible applications makes this compound a noteworthy topic for study.

Synonyms
AKOS009145516