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Amitraz

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Identification
Molecular formula
C19H23Cl2N3
CAS number
33089-61-1
IUPAC name
2-[2-(2,6-dichlorophenyl)ethylamino]guanidine
State
State

Solid at room temperature.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
185.00
Boiling point (Kelvin)
458.15
General information
Molecular weight
293.15g/mol
Molar mass
293.1490g/mol
Density
1.1700g/cm3
Appearence

Amitraz is typically a white or slightly yellowish crystalline solid. It is often supplied in technical-grade form, which may appear more off-white due to impurities.

Comment on solubility

Solubility of 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine

The solubility of 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine is an interesting aspect to explore, particularly in various solvents. This compound exhibits a distinct behavior when it comes to solubility:

  • Polarity Matters: The solubility of 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine is strongly influenced by the polarity of the solvent. It tends to dissolve better in polar solvents due to its polar functional groups.
  • Common Solvents: Typical solvents for this compound may include water (to some extent), methanol, and ethanol. Each of these solvents can offer varying degrees of solubility.
  • Limited Solubility in Non-Polar Solvents: In contrast, the compound shows poor solubility in non-polar solvents such as hexane or toluene.
  • pH Sensitivity: The solubility may also vary with changes in pH, which can affect the ionization of the guanidine group, enhancing its solubility in aqueous environments.

In summary, the solubility of 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine is predominantly affected by the polarity of the solvent and the pH of the solution, making it an intriguing compound for further examination in both research and application contexts.

Interesting facts

Interesting Facts about 2-[2-(2,6-Dichlorophenyl)ethylamino]guanidine

The compound 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine is a fascinating molecule known for its pharmacological properties. Here are some key points that highlight its significance:

  • Pharmacological Relevance: This compound is often studied for its potential role in the treatment of various neurological disorders. Its unique structure allows it to interact with specific biological pathways, making it a candidate for therapeutic applications.
  • Structure-Activity Relationship: The 2,6-dichlorophenyl moiety is particularly interesting as the substitution pattern can significantly affect the compound's biological activity. Understanding these relationships is crucial in medicinal chemistry.
  • Amine Functionality: The presence of the ethylamino group suggests that this compound can participate in protonation and hydrogen bonding, which are essential in its interaction with biological receptors and enzymes.
  • Guanidine Role: The guanidine group in the structure is known for its basicity and nucleophilicity, properties that contribute to the compound's efficiency in biological systems.
  • Research Applications: Scientists are continually exploring the behavior of this compound in various assays to determine its effectiveness as an inhibitor or modulator in therapeutic settings.
  • Safety and Toxicology: As with many organic compounds, understanding the safety profile and potential toxic effects is critical. Ongoing studies assess its cytotoxicity and biocompatibility.

As noted by experts in the field, "The journey of discovering new compounds often leads us to unexpected therapeutic fronts." The study of 2-[2-(2,6-dichlorophenyl)ethylamino]guanidine exemplifies the intricate dance between chemistry and biology, showcasing how a single molecular change can open up new avenues in medicine.

Synonyms
BRN 0750009
GUANIDINE, (2,6-DICHLOROPHENETHYLAMINO)-
(2,6-Dichlorophenethylamino)guanidine
29096-65-9
DTXSID80183340
RefChem:346695
DTXCID90105831
SCHEMBL28985640