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Cimetidine

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Identification
Molecular formula
C10H16N6
CAS number
51481-61-9
IUPAC name
2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine
State
State
Cimetidine is commonly found in a solid state at room temperature, primarily as a crystalline powder.
Melting point (Celsius)
141.50
Melting point (Kelvin)
414.60
Boiling point (Celsius)
907.00
Boiling point (Kelvin)
1 180.00
General information
Molecular weight
252.36g/mol
Molar mass
252.3550g/mol
Density
1.2000g/cm3
Appearence

Cimetidine is typically a white to off-white crystalline powder. It may form crystals when purified from solution.

Comment on solubility

Solubility of 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine

The solubility of 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine can be quite intriguing due to its structural characteristics. This compound, featuring a guanidine core and a piperidine moiety, demonstrates varying solubility in different solvents. Here are some key points regarding its solubility:

  • Water Solubility: Typically, guanidine derivatives can exhibit moderate to high solubility in water, owing to the presence of polar functional groups.
  • Organic Solvents: The compound may also show solubility in various organic solvents like ethanol, methanol, and dichloromethane, particularly due to the hydrophobic nature of the 2,6-dimethyl-2-piperidyl group.
  • Influencing Factors: Solubility can be affected by factors such as temperature, pH, and the presence of ionic species in solution.
  • Practical Implications: Its solubility profile is significant in applications such as drug formulation, where enhanced solubility can lead to improved bioavailability.

As a general observation, it can be said that compounds like 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine are often utilized in diverse chemical environments, showcasing varied solubility behaviors that can be harnessed for specific applications. As the saying goes, “Solubility is key; it opens many doors in chemistry.”

Interesting facts

Interesting Facts about 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine

2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine is a fascinating compound that belongs to a category of organic molecules with significant pharmacological potential. This compound, often utilized in medicinal chemistry, has attracted attention for several reasons:

  • Pharmacological Applications: It is known for its role as a potential therapeutic agent, especially in the regulation of blood pressure and other cardiovascular functions.
  • Structure-Activity Relationship: The intricate design of the molecule allows researchers to study how modifications in its structure can influence biological activity. The presence of the guanidine functional group is pivotal in its physiological properties.
  • Research Interest: Scientists are actively investigating its potential as a selective ligand in receptor studies, aiding in the understanding of its metabolic pathways and interactions within biological systems.
  • In-depth Studies: Because of its unique combination of a guanidine core and a piperidine derivative, it serves as an excellent template for the development of other pharmacologically active compounds.

Furthermore, the synthesis of 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine showcases a variety of fascinating organic reactions and methodologies. The exploration of this compound not only boosts our understanding of organic synthesis but also facilitates advancements in drug discovery.

In the words of one researcher: "Each modification unveils a world of possibilities, driving the quest for more effective pharmaceuticals."

In summary, 2-[2-(2,6-dimethyl-2-piperidyl)ethyl]guanidine is more than just a compound—it's a beacon of research potential, bridging structural chemistry with cutting-edge pharmaceutical applications.