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Methoxamine hydrochloride

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Identification
Molecular formula
C14H24ClNO2
CAS number
496-19-5
IUPAC name
2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride
State
State

This compound is typically found as a solid at room temperature. Methoxamine hydrochloride is handled as a crystalline powder in pharmaceutical formulations.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
242.00
Boiling point (Kelvin)
515.15
General information
Molecular weight
291.81g/mol
Molar mass
291.8060g/mol
Density
1.1500g/cm3
Appearence

Methoxamine hydrochloride appears as a white or almost white crystalline powder. It is soluble in water, making it easy to dissolve for medical applications.

Comment on solubility

Solubility of 2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride

The solubility of the compound 2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride is influenced by its ionic nature and the presence of specific functional groups. Here are some crucial points to consider:

  • Ionic vs. Non-Ionic: As a chloride salt, this compound likely exhibits good solubility in polar solvents like water due to the ionic interaction with water molecules.
  • Hydrophilic Characters: The presence of multiple hydroxyl (-OH) groups and ethoxy segments enhances its hydrophilicity, promoting interactions with water.
  • Solvent Specificity: Solubility may vary significantly in different solvents. For example, it may be less soluble in non-polar solvents like hexane.
  • Temperature Dependence: Solubility can be temperature-dependent. Typically, increasing temperature results in increased solubility for many ionic compounds.
  • pH Influence: The solubility may also exhibit alterations in varying pH conditions due to potential protonation or deprotonation of the functional groups.

As a general rule, one can conclude that compounds with large polar sites tend to have superior solubility characteristics in polar media. Thus, 2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride is expected to demonstrate good solubility in aqueous environments, contributing to its potential applications in various fields.

Interesting facts

Interesting Facts about 2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride

This compound exhibits unique characteristics that make it an intriguing subject of study in the field of chemistry. Below are some noteworthy points regarding its structure and potential applications:

  • Structural Complexity: The compound features a complex organic structure characterized by the presence of a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle. This ring contributes to the compound's stereochemistry and reactivity, making it a valuable subject for synthetic chemists.
  • Biological Relevance: Compounds with similar structures have been explored for their potential applications in neuropharmacology. The presence of the methoxyphenyl group hints at possible interactions with neurotransmitter systems, making it a candidate for research in drug development targeting neurological disorders.
  • Ionization Potential: The quaternary ammonium nature of the pyrrolidine moiety indicates this compound could behave as a charged species in solution, potentially influencing its biological activity and solubility, a crucial aspect for pharmacokinetics.
  • Synthesis Pathways: Understanding the synthetic routes to obtain this compound can provide insights into modern organic synthesis techniques, showcasing methods such as alkylation and ether formation, which are essential for constructing complex molecules.
  • Potential for Functionalization: Due to its versatile functional groups, this compound can potentially undergo further modifications to enhance its efficacy or alter its properties for specific applications, opening avenues in medicinal chemistry.

As stated by chemist Derek Lowe, "The best drugs often come from an unexpected place." This compound embodies that ethos, serving as a reminder of the vast potential awaiting discovery in the world of chemical compounds.

Overall, the study of 2-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethoxy]ethanol;chloride not only enriches our understanding of complex chemical entities but also paves the way for future innovations in pharmaceuticals.

Synonyms
Ethanol, 2-(2-(3-(m-methoxyphenyl)-3-propyl-1-pyrrolidinyl)ethoxy)-, hydrochloride
1507-64-8
1-(2-(2-Hydroxyethoxy)ethyl)-3-(m-methoxyphenyl)-3-propylpyrrolidine hydrochloride
Pyrrolidine, 1-(2-(2-hydroxyethoxy)ethyl)-3-(m-methoxyphenyl)-3-propyl-, hydrochloride