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Nebivolol

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Identification
Molecular formula
C22H26N2O4
CAS number
99200-09-6
IUPAC name
2-[2-(3-methoxy-2-propoxy-phenyl)ethyl-[2-(propylcarbamoyloxy)ethyl]amino]ethyl N-propylcarbamate
State
State

At room temperature, Nebivolol is typically in a solid state, appearing as a powder.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.00
Boiling point (Celsius)
553.20
Boiling point (Kelvin)
826.20
General information
Molecular weight
402.47g/mol
Molar mass
402.4770g/mol
Density
1.2200g/cm3
Appearence

Nebivolol appears as a white to off-white powder. It is sensitive to trace moisture and light, and hence generally encountered in its powdered form in pharmaceutical preparations.

Comment on solubility

Solubility of 2-[2-(3-methoxy-2-propoxy-phenyl)ethyl-[2-(propylcarbamoyloxy)ethyl]amino]ethyl N-propylcarbamate

The solubility of 2-[2-(3-methoxy-2-propoxy-phenyl)ethyl-[2-(propylcarbamoyloxy)ethyl]amino]ethyl N-propylcarbamate can be influenced by several factors due to its complex structure. Here are some key considerations:

  • Polarity: The presence of polar functional groups, such as carbamate and amine functionalities, suggests that this compound may exhibit reasonable solubility in polar solvents like water and methanol.
  • Hydrophobic regions: The alkyl chains and aromatic components imply that the compound might also have hydrophobic properties, potentially limiting its solubility in aqueous environments.
  • Temperature dependence: Solubility often varies with temperature; therefore, higher temperatures could enhance solubility due to increased kinetic energy disrupting intermolecular interactions.
  • pH levels: Changes in pH can affect the ionization state of the amine group, which can further influence solubility in different solvents.

In summary, while it is feasible that 2-[2-(3-methoxy-2-propoxy-phenyl)ethyl-[2-(propylcarbamoyloxy)ethyl]amino]ethyl N-propylcarbamate has significant solubility in polar solvents, the balance between its hydrophilic and hydrophobic characteristics makes it essential to experiment to determine its precise solubility parameters. As stated, “the solubility of a compound is deeply rooted in its molecular structure,” and in this case, the complexity and variety of functional groups introduce a fascinating interplay between solubility dynamics.

Interesting facts

Interesting Facts about 2-[2-(3-methoxy-2-propoxy-phenyl)ethyl-[2-(propylcarbamoyloxy)ethyl]amino]ethyl N-propylcarbamate

This compound, though complex in its structure, showcases the fascinating diversity of organic chemistry, particularly in the realm of medicinal chemistry. Here are some engaging insights into this intriguing compound:

  • Pharmacological Potential: This compound is a part of a larger class of molecules that may exhibit significant biological activity. Such compounds are often investigated for their potential use in drug development, targeting numerous health conditions.
  • Diverse Functional Groups: The structure contains various functional groups, such as carbamates and amines. Each of these groups contributes to the compound's chemical reactivity and properties, making it a rich subject for research.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the structure can enhance or diminish biological activity can provide essential insights in medicinal chemistry. This compound is an excellent candidate for SAR studies.
  • Potential Applications: Given its complex nature, this compound may have applications in therapeutics such as analgesics, anti-inflammatory agents, or even in other medicinal fields. Research into its effects could lead to benefits in treating various ailments.
  • Novelty: The synthesis of such a compound often involves advanced organic synthesis techniques, showcasing the creativity and skill of chemists in developing novel structures that could pave the way for innovative therapies.

The study of compounds like this not only enhances our understanding of chemical behavior but also opens doors to new possibilities in the field of drug discovery. As scientists delve deeper into the examination of such complex molecules, we can look forward to exciting developments that may arise from their unique chemical properties!