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Diclofenac

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Identification
Molecular formula
C14H11Cl2NO2
CAS number
15307-86-5
IUPAC name
2-[2-[(3,4-dichlorobenzoyl)amino]-4-methyl-phenoxy]acetic acid
State
State

At room temperature, diclofenac is in a crystalline solid state. It is stable under normal conditions of use and storage.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
318.13g/mol
Molar mass
318.1290g/mol
Density
1.5410g/cm3
Appearence

Diclofenac is typically found as a white to slightly yellow crystalline powder. It is commonly available in the form of tablets, gels, and injectable solutions for medical purposes. The powder form is practically insoluble in water but soluble in organic solvents like ethanol.

Comment on solubility

Solubility of 2-[2-[(3,4-dichlorobenzoyl)amino]-4-methyl-phenoxy]acetic acid

The solubility of 2-[2-[(3,4-dichlorobenzoyl)amino]-4-methyl-phenoxy]acetic acid can be influenced by several factors, making this compound particularly interesting in the context of chemistry. Overall, solubility characteristics can vary significantly based on:

  • Temperature: Solubility often increases with temperature; this compound may dissolve better in warm solvents.
  • Solvent Polarity: As an acidic compound, it is more likely to be soluble in polar solvents like water or alcohols, whereas solubility in non-polar solvents may be limited.
  • pH Levels: Since this compound contains a carboxylic acid group, its ionization can be affected by pH, potentially increasing solubility in basic solutions where it can deprotonate.

In its solid form, it may exhibit reduced solubility, as is common with many organic acids. Thus, the following observations are noteworthy regarding its solubility:

  • Limited Solubility: Generally shows lower solubility in neutral pH environments.
  • Increased Solubility: More soluble in alkaline conditions due to ionization.
  • Temperature Dependency: Enhanced solubility at increased temperatures.

As a summary, the solubility of this compound is multifaceted, affected by a combination of temperature, solvent choice, and pH levels. Understanding these variables is essential for applications in chemical research and industry.

Interesting facts

Interesting Facts about 2-[2-[(3,4-dichlorobenzoyl)amino]-4-methyl-phenoxy]acetic acid

This complex compound is an intriguing example of a synthetic chemical with diverse applications in various fields such as agrochemicals and pharmaceuticals. Here are some compelling details about this compound:

  • Structure and Functionality: The compound features a unique arrangement of functional groups, including an acetic acid moiety and an amine group linked to a dichlorobenzoyl unit. This specific structure contributes to its potential reactivity and interactions with biological systems.
  • Role in Agriculture: Compounds like this one have gained attention in agronomy due to their herbicidal properties, aiding in the effective control of unwanted vegetation, which is critical in food production.
  • Medicinal Chemistry: Its synthesis may lead to derivatives that exhibit useful pharmacological properties, opening avenues for the development of new therapeutic agents.
  • Research Impact: This compound plays a crucial role in ongoing research focused on optimizing crop yields and improving pest management strategies while minimizing environmental impact.
  • Synthesis: The creation of this compound involves multi-step synthetic pathways where specific conditions and reagents are critical for achieving the desired results.

As scientists continue to explore the potential of such complex compounds, they highlight the intersection of organic chemistry and practical applications in agriculture and medicine. In the words of a famous chemist, "The beauty of chemistry lies in its ability to create the complex from the simple." This compound embodies that philosophy.

Synonyms
BRN 2397412
ACETIC ACID, ((2-(3,4-DICHLOROBENZAMIDO)-p-TOLYL)OXY)-
6548-54-5
((2-(3,4-Dichlorobenzamido)-p-tolyl)oxy)acetic acid
DTXSID40215797
DTXCID70138288