Skip to main content

Trifluoperazine

ADVERTISEMENT
Identification
Molecular formula
C21H24F3N3O2S
CAS number
117-89-5
IUPAC name
2-[2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethoxy]ethanol
State
State

At room temperature, trifluoperazine is in a solid state. It is usually supplied in the form of tablets or capsules for pharmaceutical applications, particularly as an antipsychotic medication.

Melting point (Celsius)
244.00
Melting point (Kelvin)
517.15
Boiling point (Celsius)
541.30
Boiling point (Kelvin)
814.45
General information
Molecular weight
480.50g/mol
Molar mass
480.4380g/mol
Density
1.4700g/cm3
Appearence

Trifluoperazine appears as a crystalline solid that can range in color from white to off-white. It may also appear as pale yellow depending on the specific formulation or any impurities present.

Comment on solubility

Solubility of 2-[2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethoxy]ethanol

The solubility of the compound 2-[2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethoxy]ethanol is influenced by several factors, including its complex molecular structure and the presence of functional groups. Here are some important aspects to consider:

  • Polarity: The compound contains multiple polar functional groups that can interact favorably with water, potentially enhancing its solubility in polar solvents.
  • Hydrophobic Regions: The presence of aromatic rings and a trifluoromethyl group may contribute to hydrophobic characteristics, affecting solubility in nonpolar solvents.
  • Potential Solvents: It may exhibit solubility in a range of solvents, including:
    • Water
    • Alcohols (such as ethanol)
    • Chloroform
  • Examples of Solubility Behavior: Some compounds with similar structures may obey "like dissolves like" principles, meaning that they may dissolve more readily in solvents with similar polarities.

In summary, while this compound may be expected to have varying degrees of solubility in different solvents, further experimental data would provide a more definitive understanding of its solubility profile. As always, one should consider specific conditions such as temperature and pH that might affect the solubility of this intriguing chemical compound.

Interesting facts

Interesting Facts about 2-[2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethoxy]ethanol

This compound belongs to a class of chemical substances known for their complex structure and unique properties. Here are some interesting points about it:

  • Pharmacological Potential: The compound is likely to have significant pharmacological activities due to its phenothiazine core, which is a well-known framework in medicinal chemistry often associated with antipsychotic and antihistaminic properties.
  • Structural Diversity: Its intricate structure, featuring a trifluoromethyl group, aromatic rings, and piperazine moieties, contributes to its versatility. This complexity allows for interactions with various biological targets, making it a candidate for drug development.
  • Fluorine's Role: The presence of the trifluoromethyl group is particularly intriguing as it can enhance the metabolic stability and lipophilicity of the compound, which can be beneficial for pharmacokinetics.
  • Potential Applications: Research suggests that compounds of this nature could be explored for therapeutic interventions in neuropsychiatric disorders, cardiovascular diseases, and even cancer.

As a chemistry student or scientist, exploring this compound opens doors to fascinating discussions about the relationship between molecular structure and biological activity. Its design underscores the importance of strategic molecular modifications in the quest for effective therapies. The ongoing research in this field continues to highlight the *dynamic nature of chemical compound development* as we strive to create innovative solutions for complex health issues.

Synonyms
3093-23-0
2-[2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazine-10-yl]propyl]piperazino]ethoxy]ethanol
Fluorophenothiazine
CHEMBL608850
LS56B46KA3
SCHEMBL10168352
DTXSID30878658
BQVKHSWJSBZCTN-UHFFFAOYSA-N
Ethanol, 2-[2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethoxy]-
Ethanol, 2-[2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethoxy]-
NCI60_004321
ETHANOL, 2-[2-[4-[3-[2-(TRIFLUOROMETHYL)PHENOTHI
2-Trifluoromethyl-10-[3-[4-[2-(2-hydroxyethoxy)-ethyl]-1-piperazinyl]propyl]phenothiazine
2-[2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethoxy]ethanol