Bleomycin | Solubility of Things

Identification

Molecular formula

C₅₅H₈₄N₁₇O₂₁S₃

CAS number

11056-06-7

IUPAC name

[2-[2-[(4-amino-4-carboxy-butanoyl)amino]-3-(carboxymethylamino)-3-oxo-propyl]sulfanyl-5-[hydroxy(oxo)ammonio]phenyl]-hydroxy-oxo-ammonium

State

Bleomycin is a solid under normal conditions at room temperature.

Melting point (Celsius)

134.00

Melting point (Kelvin)

407.15

Boiling point (Celsius)

276.00

Boiling point (Kelvin)

549.15

General information

Molecular weight

1415.55g/mol

Molar mass

1 415.5480g/mol

Density

1.2800g/cm³

Appearence

Bleomycin typically appears as a white to pale yellow powder. It is supplied in a lyophilized (freeze-dried) form for reconstitution, primarily for research or pharmaceutical use.

Comment on solubility

Solubility of 2-[2-[(4-amino-4-carboxy-butanoyl)amino]-3-(carboxymethylamino)-3-oxo-propyl]sulfanyl-5-[hydroxy(oxo)ammonio]phenyl]-hydroxy-oxo-ammonium

The solubility of complex compounds like 2-[2-[(4-amino-4-carboxy-butanoyl)amino]-3-(carboxymethylamino)-3-oxo-propyl]sulfanyl-5-[hydroxy(oxo)ammonio]phenyl]-hydroxy-oxo-ammonium (C₅₅H₈₄N₁₇O₂₁S₃) is influenced by several factors, primarily its ionic and polar nature, as well as the presence of functional groups. Understanding solubility is essential, especially when it comes to its applications in various fields. Here are some key points to consider:

Polarity: The presence of multiple polar functional groups, such as amino and carboxylic acid groups, often enhances solubility in polar solvents like water.
Hydrogen Bonding: Compounds with the ability to form hydrogen bonds generally exhibit improved solubility, allowing them to interact favorably with solvent molecules.
Salt Formation: The ammonium group in the compound may lead to increased solubility through ionization in solution, especially in acidic conditions.
Molecular Size: With a large molecular weight, the overall solubility might be limited compared to smaller compounds, necessitating solubilization techniques when used in applications.

It is important to experiment under controlled conditions to accurately assess solubility. For example, quoting from literature: “Compounds with extensive hydrogen-bonding capabilities tend to exhibit significantly better solubility profiles in water.” Thus, considering these properties, one can surmise that this compound may demonstrate moderate to high solubility in aqueous solutions, albeit further experimental validation would be essential.

Interesting facts

Interesting Facts about 2-[2-[(4-amino-4-carboxy-butanoyl)amino]-3-(carboxymethylamino)-3-oxo-propyl]sulfanyl-5-[hydroxy(oxo)ammonio]phenyl]-hydroxy-oxo-ammonium

This fascinating compound represents a complex interplay of functional groups and intricate molecular structure that showcases the vastness of organic chemistry. As a nitrogenous compound, it is particularly intriguing due to its potential applications in various fields, including medicinal chemistry and biochemistry.

Key Features:

Multi-Functional Groups: The compound contains multiple amino, carboxy, and hydroxy groups, which are crucial for forming hydrogen bonds. This can enhance solubility and reactivity, indicating its potential significance in drug design.
Biological Relevance: The presence of amino acids within the structure suggests that it may interact with biological systems, making it interesting for research into therapeutics or as a biochemical tool.
Complex Synthesis: The multi-step synthesis required for preparing such a compound underscores the challenges and creativity inherent in organic synthesis, reflecting the sophisticated methods chemists employ in developing new materials.

According to a well-known dictum in chemistry, "The beautiful thing about learning is that no one can take it away from you." This rings particularly true when studying compounds like this one, as each functional group provides a unique opportunity to explore concepts of structure, reactivity, and function.

Moreover, the specific arrangement of elements within this molecule can lead to unique properties that are yet to be fully understood. Continued research may unlock its potential, leading to breakthroughs in fields ranging from pharmacology to materials science.

Understanding this compound's structure opens new doors to exploring its utility, making it a remarkable example of the complexities of chemical science.