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Cloperastine Hydrochloride

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Identification
Molecular formula
C23H30ClNO3
CAS number
19397-62-5
IUPAC name
2-[2-(4-chlorophenyl)-2-phenyl-1,3-dioxolan-4-yl]piperidin-1-ium;chloride
State
State

Cloperastine hydrochloride is typically found in solid form at room temperature. It is administered orally as a medication and has a crystalline state in its pure form.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.00
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.00
General information
Molecular weight
425.95g/mol
Molar mass
425.3630g/mol
Density
1.2900g/cm3
Appearence

Cloperastine hydrochloride appears as a white to slightly yellow crystalline powder. It is odorless or may have a mild characteristic odor.

Comment on solubility

Solubility of 2-[2-(4-chlorophenyl)-2-phenyl-1,3-dioxolan-4-yl]piperidin-1-ium;chloride

The solubility characteristics of 2-[2-(4-chlorophenyl)-2-phenyl-1,3-dioxolan-4-yl]piperidin-1-ium;chloride are influenced by its complex structure. This compound can be described as a quaternary ammonium salt, which generally demonstrates specific solubility traits:

  • Water Solubility: Quaternary ammonium salts often exhibit a high degree of solubility in water due to their ionic nature; hence, this compound is likely to dissolve readily in aqueous solutions.
  • Solvent Compatibility: Its solubility can also vary in organic solvents. Depending on the solvent polarity, the compound may either dissolve easily or present challenges in solvation.
  • Influence of Chlorine Substitution: The presence of the –Cl group may improve its solubility in certain organic solvents, making it more versatile in various chemical environments.

Furthermore, temperature and pH can significantly affect the solubility of this compound—higher temperatures typically enhance solubility. As such, understanding the solubility profile is key for effective application and manipulation in chemical processes.

Interesting facts

Interesting Facts about 2-[2-(4-chlorophenyl)-2-phenyl-1,3-dioxolan-4-yl]piperidin-1-ium; chloride

This compound, notable for its complex structure, offers a fascinating glimpse into the intersection of organic chemistry and medicinal chemistry. Here are some interesting facts:

  • Pharmacological Potential: Compounds that feature a piperidine moiety are often studied for their biological activity, making this compound a subject of interest in the development of new pharmaceuticals.
  • Structural Intricacies: The presence of a dioxolane ring within the compound suggests potential stereochemical diversity. This aspect may play a crucial role in how the compound interacts with biological systems.
  • Chlorine Substitution: The 4-chlorophenyl group contributes not only to the lipophilicity of the compound but also to its possible reactivity, which can enhance its pharmacological properties.
  • Stability Considerations: The synthesis of such compounds often involves careful consideration of stability and reactivity, especially in terms of substituents that can influence the overall behavior of the chemical.
  • Piperidin-ium Ion: The piperidin-1-ium functional group indicates that the compound can carry a positive charge, which could affect its solubility and interaction with biological membranes.

In summary, the complexity of 2-[2-(4-chlorophenyl)-2-phenyl-1,3-dioxolan-4-yl]piperidin-1-ium; chloride makes it a captivating subject for researchers looking into new drug design and therapeutic applications. Whether in academic research or pharmaceutical development, understanding the underlying chemistry of such compounds is essential for unlocking their potential.

Synonyms
2-(p-Chlorophenyl)-2-phenyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride
7457-28-5
1,3-DIOXOLANE, 2-(p-CHLOROPHENYL)-2-PHENYL-4-(2-PIPERIDYL)-, HYDROCHLORIDE