Interesting facts
Interesting Facts about 2-[2-[(4-ethoxyphenyl)methyl]-5-nitro-benzimidazol-1-yl]-N,N-diethyl-ethanamine
This compound is a fascinating example of a molecule that integrates elements of organic synthesis and medicinal chemistry. The structural complexity of this compound arises from its combination of a benzimidazole core and a nitro group, which plays a key role in its biological activity. Here are some key highlights:
- Versatile Structural Class: The benzimidazole structure is known for its biological significance, with many derivatives being investigated for anti-parasitic, anti-cancer, and anti-inflammatory properties.
- Nitro Group Influence: The presence of the nitro group enhances the compound's electrophilic character, which can facilitate reactions, making it an important functional group in drug design.
- Pharmacological Potential: Compounds like this one have been studied for their activity against various pathogens, demonstrating their potential in treating illnesses caused by resistant strains.
- Ethoxy Phenyl Substitution: The 4-ethoxyphenyl unit contributes to lipophilicity, possibly improving cell membrane permeability, which is crucial for the effectiveness of pharmaceuticals.
- Diethylamine Moiety: The N,N-diethyl group serves not only to enhance solubility but also plays a significant role in receptor binding interactions, essential for biological efficacy.
The intersection of organic chemistry and pharmacology is exemplified through such compounds, showcasing the importance of molecular design in the development of effective therapeutic agents. As we continue to explore these complex molecules, their potential for addressing unmet medical needs remains a critical area of research.
Synonyms
Etonitazene
Etonitazine
911-65-9
Ciba 20-684BA
Etonitazinum
ARC 1G2
Etobedolum
Etonitazeno
NIH 7607
Etonitazenum
Etonitazenum [INN-Latin]
Etonitazeno [INN-Spanish]
Etonitazene [INN:BAN:DCF]
Ba-20684
Acscn-9624
EINECS 213-009-1
UNII-9U3GT3353T
BRN 0363324
IDS-NE-006
DTXSID6048919
9U3GT3353T
1H-Benzimidazole-1-ethanamine, 2-((4-ethoxyphenyl)methyl)-N,N-diethyl-5-nitro-
NIH-7607
ETONITAZENE [MI]
ETONITAZENE [INN]
1-(2-Diethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole
1-(2-(Diethylamino)ethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole
ETONITAZENE [WHO-DD]
DTXCID3028845
5-23-12-00348 (Beilstein Handbook Reference)
Etonitazene (INN)
2-[2-[(4-ethoxyphenyl)methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
etonitazin
Benzimidazole, 1-[2-(diethylamino)ethyl]-2-(p-ethoxybenzyl)-5-nitro-
Etonitazenum (INN-Latin)
1H-Benzimidazole-1-ethanamine, 2-[(4-ethoxyphenyl)methyl]-N,N-diethyl-5-nitro-
BENZIMIDAZOLE, 1-(2-(DIETHYLAMINO)ETHYL)-2-(p-ETHOXYBENZYL)-5-NITRO-
Etonitazeno (INN-Spanish)
(2-(2-((4-ethoxyphenyl)methyl)-5-nitro-1H-1,3-benzodiazol-1-yl)ethyl)diethylamine
(2-{2-[(4-ethoxyphenyl)methyl]-5-nitro-1H-1,3-benzodiazol-1-yl}ethyl)diethylamine
2-(2-((4-ethoxyphenyl)methyl)-5-nitrobenzimidazol-1-yl)-N,N-diethylethanamine
1H-Benzimidazole-1-ethanamine, 2-((4-ethoxyphenyl)methyl)-N,N-diethyl-5-nitro-(9CI)
213-009-1
pxdbzscgsqskst-uhfffaoysa-n
CHEMBL312040
{2-[2-(4-Ethoxy-benzyl)-5-nitro-benzoimidazol-1-yl]-ethyl}-diethyl-amine
Ba 20684
DEA No. 9624
SCHEMBL25183
GTPL1624
Tox21_112830
BDBM50013847
PDSP1_001558
PDSP2_001542
CS-6622
DB01462
CAS-911-65-9
HY-101645
NS00039388
D12669
L000697
Q5404835
2-[2-(4-Ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl]-N,N-diethylethanamine #
Solubility of 2-[2-[(4-ethoxyphenyl)methyl]-5-nitro-benzimidazol-1-yl]-N,N-diethyl-ethanamine
The solubility of 2-[2-[(4-ethoxyphenyl)methyl]-5-nitro-benzimidazol-1-yl]-N,N-diethyl-ethanamine can be described as follows:
Overall, understanding the solubility behavior of this compound is crucial for its practical applications, especially in contexts such as pharmaceutical formulations where solubility can directly impact bioavailability. In conclusion, while this compound may face challenges in aqueous environments, its increased solubility in organic solvents makes it a fascinating subject for further exploration.