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Ebastine

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Identification
Molecular formula
C32H39ClN2O2
CAS number
90729-43-4
IUPAC name
2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]-N,N-diethyl-ethanamine
State
State

Ebastine is typically a solid at room temperature.

Melting point (Celsius)
72.50
Melting point (Kelvin)
345.70
Boiling point (Celsius)
527.15
Boiling point (Kelvin)
800.30
General information
Molecular weight
469.62g/mol
Molar mass
469.6200g/mol
Density
1.0872g/cm3
Appearence

Ebastine appears as a white to slightly yellowish crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]-N,N-diethyl-ethanamine

The solubility of 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]-N,N-diethyl-ethanamine is influenced by its unique chemical structure which comprises both hydrophobic and hydrophilic characteristics. This compound is expected to have variable solubility depending on the solvent used, leading to the following insights:

  • Polar Solvents: It may exhibit moderate solubility in polar solvents such as water due to the presence of polar functional groups in its structure.
  • Nonpolar Solvents: In contrast, the aromatic rings and ethoxy group may increase solubility in nonpolar solvents like hexane or chloroform.
  • pH Dependency: The solubility could also be affected by the pH of the solution, especially if protonation or deprotonation of any nitrogen atoms occurs, potentially enhancing its solubility at certain pH levels.
  • Temperature Effects: Generally, it can be anticipated that increasing the temperature might enhance solubility, a common behavior for many organic compounds.

Understanding the solubility characteristics of this compound is essential for practical applications such as drug formulation and material science where solubility plays a crucial role. As emphasized: "Solubility is a key determinant of a compound's usability in various chemical processes."

Interesting facts

Interesting Facts about 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]-N,N-diethyl-ethanamine

This fascinating compound belongs to a class of molecules that exhibit significant biological activity, particularly in the field of medicinal chemistry. Here are some engaging insights about this compound:

  • Structure and Function: The unique architecture of this compound features a benzimidazole core, which is crucial for its biological activity, especially in pharmaceutical applications. Benzimidazoles are known for their ability to interact with various biological targets, including enzymes and receptors.
  • Biological Relevance: Compounds like this one have been studied for their potential anti-cancer, anti-inflammatory, and antimicrobial properties. The presence of a sulfonyl group often enhances the interaction of such compounds with biological systems, leading to improved efficacy.
  • Pharmacological Potential: Due to its diverse functional groups, this compound may demonstrate a range of pharmacological effects. The ethoxyphenyl group could potentially contribute to its lipophilicity, influencing its pharmacokinetics and bioavailability.
  • Research Insights: Scientists are continually exploring the synthesis and modification of similar compounds to enhance their therapeutic properties. *"Understanding the structure-activity relationship is key in medicinal chemistry,"* says a noted chemist, highlighting the importance of chemical structure in determining a compound’s effectiveness.
  • Synthesis Challenges: The synthesis of such complex molecules is often fraught with challenges including reaction conditions and purification processes. Chemists utilize advanced techniques in organic synthesis to achieve desirable yields and purity levels.

In summary, 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]-N,N-diethyl-ethanamine is not just a compound of interest; it represents the intersection of structure, function, and biological activity that is fundamental to the development of new therapeutic agents.

Synonyms
QVU7FQ2TVH
UNII-QVU7FQ2TVH
3275-92-1
1-(2-(Diethylamino)ethyl)-2-((p-ethoxyphenyl)thio)benzimidazole
1H-Benzimidazole-1-ethanamine, 2-((4-ethoxyphenyl)thio)-N,N-diethyl-
2-((4-Ethoxyphenyl)thio)-N,N-diethyl-1H-benzimidazole-1-ethanamine
Benzimidazole, 1-(2-(diethylamino)ethyl)-2-((p-ethoxyphenyl)thio)-