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Ebastine

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Identification
Molecular formula
C32H39ClN2O2S
CAS number
107667-60-7
IUPAC name
2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]ethyl-diethyl-ammonium;chloride
State
State

At room temperature, Ebastine is in a solid state.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.00
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.00
General information
Molecular weight
469.06g/mol
Molar mass
469.0630g/mol
Density
1.1800g/cm3
Appearence

Ebastine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]ethyl-diethyl-ammonium;chloride

The solubility of the compound 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]ethyl-diethyl-ammonium;chloride can offer interesting insights into its behavior in different environments. Having a complex structure that includes both organic and ionic characteristics, its solubility is largely influenced by factors such as:

  • Polarity: The presence of the ammonium group contributes to its ionic nature, which typically increases solubility in polar solvents like water.
  • Hydrophobic interactions: The ethoxyphenyl and benzimidazole components may create hydrophobic regions, impacting solubility in non-polar solvents.
  • Temperature: Higher temperatures generally enhance solubility, allowing more chlorides to dissociate in solution.
  • pH levels: Adjusting the pH can alter the ionization of the ammonium group, significantly affecting its solubility profile.

As noted in various studies, compounds with similar structures often demonstrate solubility behaviors where ionic interactions dominate in aqueous environments, while their hydrophobic components could lead to limited solubility in organic solvents. Thus, understanding these relationships is crucial for predicting the solubility of this compound in practical applications.

Overall, assessing the solubility of this compound is essential for its potential use in pharmaceuticals, as solubility directly influences bioavailability and therapeutic effectiveness.

Interesting facts

Interesting Facts about 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]ethyl-diethyl-ammonium;chloride

This remarkable compound is known for its unique structural features and potential applications in various fields. Here are some intriguing aspects of this compound:

  • Complex Structure: The compound contains a benzimidazole core, which is a fascinating structure due to its presence in numerous biologically active molecules. The presence of a sulfanyl group adds reactivity, making this compound a subject of study in medicinal chemistry.
  • Pharmacological Potential: Compounds with benzimidazole structures are often investigated for their pharmacological properties. They may exhibit activities such as antimicrobial, antiviral, or anticancer effects, potentially leading to the development of new therapeutic agents.
  • Ammonium Ion: The diethylammonium moiety in the compound enhances its solubility and may influence biological activity due to its positive charge, facilitating interaction with various biological targets.
  • Sulfanyl Group: The sulfanyl (thioether) functionality can significantly impact the compound's reactivity and stability. This feature can be beneficial in constructing more complex chemical architectures through various reactions.
  • Applications in Research: Researchers are exploring the compound for its potential use in drug delivery systems and as a component in advanced materials due to its favorable chemical properties.

In summary, 2-[2-(4-ethoxyphenyl)sulfanylbenzimidazol-1-yl]ethyl-diethyl-ammonium;chloride showcases a fascinating blend of chemical features that make it an exciting compound in scientific research. Its diverse applications and interesting functionalities give it a noteworthy position in the study of chemical compounds.

Synonyms
Benzimidazole, 1-(2-(diethylamino)ethyl)-2-((p-ethoxyphenyl)thio)-, hydrochloride
1-(2-(Diethylamino)ethyl)-2-((p-ethoxyphenyl)thio)benzimidazole hydrochloride
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