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Nimorazole

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Identification
Molecular formula
C9H10FN3O3
CAS number
6506-37-2
IUPAC name
2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol
State
State

At room temperature, Nimorazole exists as a solid. It is stable under standard conditions but should be stored in a cool, dry place away from direct sunlight and moisture to maintain its integrity.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
596.15
Boiling point (Kelvin)
869.30
General information
Molecular weight
270.19g/mol
Molar mass
270.2240g/mol
Density
1.4000g/cm3
Appearence

Nimorazole typically appears as a white to pale yellow crystalline powder. It is odorless and has a bitter taste. The compound is used in pharmaceuticals and it is important for it to be free from any discolorations or impurities that might affect its efficacy.

Comment on solubility

Solubility of 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol

The solubility of 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol, a compound with significant implications in various chemical and pharmaceutical applications, can be further understood by considering the following factors:

Key Points on Solubility

  • Polarity: This compound contains both hydrophilic ethanol and more hydrophobic aromatic nitro substituents, which may influence its overall solubility in water and organic solvents.
  • Solvent Compatibility: Depending on the solvent used (e.g., water, ethanol, DMSO), the solubility can vary greatly. It is generally expected to be more soluble in polar solvents.
  • Temperature Effects: Increased temperatures often enhance solubility, which may improve the dissolution of 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol in particular solvents.

Researchers often state: "Understanding the solubility parameters of compounds is critical for their practical applications." Thus, the solubility of 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol is not only reliant on its structural components but also on the environmental factors such as temperature and solvent choice. Proper assessment of solubility can lead to more effective utilization in biochemical contexts and can drive further investigations in drug development.

Interesting facts

Interesting Facts about 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol

2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol is a fascinating compound with noteworthy applications and properties. Here are some interesting facts about this complex molecule:

  • Pharmacological Potential: This compound possesses significant pharmacological activity due to its unique imidazole structure, which is renowned for being a core component in many bioactive compounds.
  • Cancer Research: 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol is particularly interesting in cancer research. Its composition allows it to interact with biological pathways relevant to tumor growth and progression, making it a candidate for further studies in anti-cancer therapies.
  • Fluorine's Role: The presence of the fluorine atom in the structure enhances the metabolic stability of the compound. Fluorinated compounds often exhibit increased lipophilicity and improved bioavailability, which can lead to better pharmacokinetic properties.
  • Research Applications: Due to its specificity and activity, this compound is often used in research settings to study enzymatic reactions and mechanisms in biological systems.
  • Structure-Activity Relationship: The detailed study of this compound fosters a better understanding of structure-activity relationships (SAR) in medicinal chemistry. Researchers investigate how variations in the chemical structure can influence biological activity.

In summary, 2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol is more than just a chemical compound; it acts as a bridge connecting chemistry, pharmacology, and potential therapeutic advances, highlighting the intricate beauty of chemical research.

Synonyms
FLUNIDAZOLE
4548-15-6
Flunidazol
2-[2-(4-fluorophenyl)-5-nitroimidazol-1-yl]ethanol
1H-Imidazole-1-ethanol, 2-(4-fluorophenyl)-5-nitro-
5-NI
2-(p-Fluorophenyl)-5-nitroimidazole-1-ethanol
NSC-323560
Imidazole-1-ethanol, 2-(p-fluorophenyl)-5-nitro-
I047971MRN
MK-915
NSC323560
2-[2-(4-fluoro-phenyl)-5-nitro-imidazol-1-yl]-ethanol
5-NI; MK-915; NSC 323560
Flunidazolum
Flunidazol [INN-Spanish]
Flunidazole [USAN:INN]
Flunidazolum [INN-Latin]
UNII-I047971MRN
NSC 323560
FLUNIDAZOLE [INN]
Flunidazole (USAN/INN)
FLUNIDAZOLE [USAN]
FLUNIDAZOLE [WHO-DD]
SCHEMBL636164
CHEMBL2105090
DTXSID50196523
AKOS015905895
DS-002879
NS00124142
D04213
1H-imidazole-1-ethanol,2-(4-fluorophenyl)-5-nitro-
2-(2-(p-Fluorophenyl)-5-nitroimidazol-1-yl)ethanol
2-[2-(4-fluorophenyl)-5-nitro-imidazol-1-yl]ethanol
Q27280186
2-(2-(4-Fluorophenyl)-5-(hydroxy(oxido)amino)-1H-imidazol-1-yl)ethanol