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Descarboxylated Pimagedine

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Identification
Molecular formula
C10H20N4
CAS number
53549-36-5
IUPAC name
2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine
State
State

At room temperature, it is a solid. Due to its crystalline nature, it is likely to have a distinct lattice structure which imparts its solid characteristic at room temperature.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
183.29g/mol
Molar mass
183.2940g/mol
Density
1.0300g/cm3
Appearence

The compound is typically a white to off-white crystalline solid, suggesting its purity and indicating some level of hygroscopic nature, as is common with similar guanidine derivatives.

Comment on solubility

Solubility of 2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine

When discussing the solubility of 2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine, several factors come into play:

  • Polarity: The presence of multiple functional groups in the molecule affects its solubility. The guanidine group is known to be polar, which generally increases solubility in polar solvents such as water.
  • Hydrogen bonding: The ability of this compound to form hydrogen bonds with solvent molecules can enhance solubility. Compounds that can form hydrogen bonds often have greater solubility in polar solvents.
  • Hydrophobic character: The methyl and cyclic pyridine portions may introduce some hydrophobic character, potentially decreasing solubility in highly polar solvents.

In summary, the solubility of this compound is expected to be moderate, with greater solubility in polar solvents due to its polar nature and ability to engage in hydrogen bonding. However, the presence of hydrophobic regions may limit its solubility in very polar environments. It is important to consider specific experimental conditions, such as temperature and concentration, to assess its solubility more accurately.

Interesting facts

Interesting Facts About 2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine

2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine, often referred to in scientific literature for its biological significance, is a compound of great interest in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound falls into the category of guanidines, which are known for their diverse biological activities. Compounds of this type can interact with various biological targets, making them crucial in drug development.
  • Synthesis and Structure: The synthetic pathway to create this compound often involves the reaction of guanidine derivatives with pyridine. The resulting structure is characterized by its unique nitrogen-rich framework that contributes to its pharmacological properties.
  • Potential Therapeutic Uses: Research indicates that guanidine derivatives can possess neuroprotective and anti-inflammatory properties. This compound may present potential therapeutic avenues for neurological disorders or chronic inflammatory conditions.
  • Research Insight: According to studies, compounds with structural similarities to 2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine show promise as selective modulators of various receptors in the body, which could lead to drug candidates with enhanced efficacy and reduced side effects.

In summary, 2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine exemplifies the intricate relationship between structure and biological function. As research continues, the exploration of this compound could unveil significant contributions to pharmacology and medicinal chemistry.

Synonyms
Guanacline
1463-28-1
Guanaclina
Guanacline [INN]
Cyclazenine
2-[2-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]guanidine
2S93M1DW13
(2-(3,6-Dihydro-4-methyl-1(2H)-pyridyl)ethyl)guanidine
Guanaclinum
Guanidine, (2-(3,6-dihydro-4-methyl-1(2H)-pyridinyl)ethyl)-
Guanacline [INN:BAN]
Guanaclinum [INN-Latin]
Guanaclina [INN-Spanish]
UNII-2S93M1DW13
GUANACLINE [MI]
GUANACLINE [WHO-DD]
SCHEMBL309588
CHEMBL1160385
DTXSID90163350
CHEBI:134825
2-[2-(4-methyl-3,4-dihydro-2H-pyridin-1-yl)ethyl]guanidine; sulfuricacid
AKOS006273429
Q27255539