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Furazolidone

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Identification
Molecular formula
C12H8N2O5
CAS number
67-45-8
IUPAC name
2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid
State
State

At room temperature, Furazolidone is typically found in the solid state.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
225.21g/mol
Molar mass
225.2060g/mol
Density
1.6900g/cm3
Appearence

Furazolidone is a yellow to yellow-orange crystalline powder.

Comment on solubility

Solubility of 2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid

The solubility characteristics of 2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid can be intricate due to its complex structure, which includes a quinoline ring and an electron-withdrawing nitro group. Here are some pertinent points regarding its solubility:

  • Polar vs. Nonpolar Solvents: This compound may exhibit greater solubility in polar solvents due to the carboxylic acid functional group, which can engage in hydrogen bonding.
  • Aqueous Solubility: The solubility in water is typically limited, as the large organic framework tends to dominate its solvation behavior.
  • Miscibility: The compound may be expected to be less miscible with nonpolar solvents owing to its polar nature.
  • Temperature Influence: Solubility is likely to increase with temperature, though specific solubility data at different temperatures would provide clearer insights.

As with many organic compounds, the aforementioned factors contribute to its solubility profile, which is critical for applications in pharmaceutical formulations and material sciences. Further investigation is warranted to quantify its solubility in various solvents and under different conditions to optimize its use in practical applications.

Interesting facts

Interesting Facts about 2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid

2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid is an intriguing compound that blends the fascinating chemistry of quinolines with the unique properties of nitrofurans. This compound stands out not only for its structural complexity but also for its potential applications in various fields.

Key Features of the Compound:

  • Antimicrobial Properties: The presence of the nitro group in the furan ring suggests potential antimicrobial activity, which could be useful in developing new antibiotics.
  • Versatile Chemistry: Quinoline derivatives are known for their ability to participate in numerous chemical reactions, making this compound an excellent candidate for further chemical modifications.
  • Fluorescent Properties: Some quinoline derivatives exhibit fluorescence, which can be leveraged in biological imaging and sensing applications.
  • Bioactivity: Research suggests that compounds with similar structures may show promise in the treatment of various diseases, particularly those related to cancer.

The molecule's design promotes investigation into its biological properties, with scientists exploring its mechanisms of action. It serves as a testament to the creativity and complexity present in the field of organic chemistry. As one researcher aptly put it, “The intricacies of such compounds often unlock new pathways in both chemical synthesis and medical treatment.”

Given its unique structure, 2-[2-(5-nitro-2-furyl)vinyl]quinoline-4-carboxylic acid represents a bridge between theoretical chemistry and practical applications, inviting scientists to delve deeper into its properties and potential uses.

Synonyms
2-[2-(5-NITRO-FURAN-2-YL)-VINYL]-QUINOLINE-4-CARBOXYLIC ACID
SCHEMBL11418329
DB-364480
2-(5-nitrofurylvinyl)quinoline-4-carboxylic acid