Skip to main content

Brimonidine

ADVERTISEMENT
Identification
Molecular formula
C11H10BrN5O2
CAS number
59803-98-4
IUPAC name
2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine
State
State

At room temperature, Brimonidine is typically found in a solid state.

Melting point (Celsius)
285.00
Melting point (Kelvin)
558.00
Boiling point (Celsius)
640.00
Boiling point (Kelvin)
913.00
General information
Molecular weight
292.14g/mol
Molar mass
292.1350g/mol
Density
1.8000g/cm3
Appearence

Brimonidine is typically observed as a white to off-white crystalline powder.

Comment on solubility

Solubility Insights for 2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine

The solubility of 2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine is influenced by various factors, given its complex structure. Understanding the solubility behavior can provide insights into its potential applications and interactions in different environments.

Factors Affecting Solubility:

  • Polarity: The presence of the guanidine functional group suggests it is relatively polar, which may enhance solubility in polar solvents like water.
  • Hydrophobic Regions: The 6-bromo-1,3-benzodioxole structure adds a hydrophobic character, which may limit solubility in non-polar solvents.
  • Concentration: As with many compounds, an increase in temperature can result in higher solubility due to increased molecular movement.
  • pH of the Medium: The solubility of guanidine derivatives can be affected by the pH of the solution, as it may become protonated in acidic conditions.

Moreover, it is often observed that compounds with benzodioxole moieties may exhibit unique solubility behaviors, likely arising from their ability to form hydrogen bonds and potential interactions with surrounding molecules.

To sum it up, while the overall solubility of 2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine suggests greater affinity for polar solvents, it is essential to consider the combined effects of its structural features and the conditions present during dissolution.

Interesting facts

Interesting Facts about 2-[2-(6-Bromo-1,3-benzodioxol-5-yl)ethyl]guanidine

The compound 2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine is a fascinating member of the guanidine class, known for its potential biological activities and unique structural features. Here are some intriguing insights into this compound:

  • Biological Activity: This guanidine derivative is often studied for its pharmacological properties, particularly its influence on neurotransmitter systems. It may exhibit antidepressant and anxiolytic effects, making it of great interest in medicinal chemistry.
  • Structural Significance: The presence of the benzodioxole moiety in this compound contributes to its unique properties. This fused ring system is known for its role in various bioactive natural products, often lending itself to important interactions in biological systems.
  • Substituent Impacts: The incorporation of the bromo group at the 6-position enhances the electronic properties of the compound, potentially increasing its reactivity and altering its binding affinity to biological targets.
  • Chemical Interactions: Guanidine derivatives like this are known to participate in hydrogen bonding and electrostatic interactions, making them versatile candidates for drug design. Their ability to form such interactions can lead to increased efficacy in targeting specific receptors.

In summary, 2-[2-(6-bromo-1,3-benzodioxol-5-yl)ethyl]guanidine stands out not only for its complex structure but also for its potential implications in the field of pharmaceuticals. As research continues to unveil the intricacies of its biological effects, this compound exemplifies the interplay between structure and function in medicinal chemistry.